Publications by authors named "Chen-Hsin Tsai"
Purpose: We evaluated the IOP-lowering efficacy and safety of latanoprostene bunod (LBN) ophthalmic solution 0.024% (Vyzulta®), the first topical nitric oxide-donating prostaglandin analog (PGA), in clinical practice.
Materials And Methods: A retrospective medical chart review from July 2021 to July 2023 of patients with open-angle glaucoma receiving LBN with at least 1 year follow-up was conducted.
Article Synopsis
- Human alpha-enolase (hEno1) is overexpressed in various cancers and linked to poor prognosis, making it a valuable biomarker and treatment target.
- Polyclonal IgY antibodies from chickens immunized with hEno1 showed a strong immune response, and phage display technology created two libraries of antibody fragments with a high number of transformants.
- Selected anti-hEno1 antibody fragments (scFvs) effectively bound to hEno1 on lung cancer cells and significantly inhibited their growth and migration, suggesting potential for cancer diagnostics and therapy.
Enterovirus 71 (EV71) is the major etiological agent contributing to the development of hand-foot-mouth disease (HFMD). There are not any global available vaccines or antibody drugs against EV71 released yet. In this study, we perform the virus immunization in a cost-effective and convenient approach by preparing virus particles from size exclusion and immunization of chicken.
View Article and Find Full Text PDFBackground: The aim of this study was to determine the use of flexible iris retractors in four patients with zonular dialysis occurring during cataract surgery.
Methods: We describe the use of flexible iris retractors to stretch and fixate the capsulorhexis over the zonular dehiscence sector for patients with traumatic zonular disruption occurring during phacoemulsification, which stabilizes the capsular bag and facilitates cataract extraction without complications.
Results: Each of the four eyes was implanted with posterior chamber intraocular lens (PCIOL) successfully.
Purpose: To describe clinical features, predisposing factors, and surgical outcomes of retinal detachment in different age groups in a pediatric population.
Design: Retrospective, noncomparative, interventional case series.
Participants: A total of 296 eyes from 278 children younger than 18 years of age underwent the first surgical procedure for rhegmatogenous retinal detachment between 1983 and 2003.
Background: We report on the experience of retinopathy of prematurity (ROP) at Chang Gang Memorial Hospital (CGMH), Keelung, Taiwan over a 10-year period.
Methods: A retrospective review was made of data of all premature infants with a diagnosis of ROP at Keelung CGMH between 1994 and 2003. Data on certain characteristics including gender, gestational age (GA), birth body weight (BBW), stage of ROP, and treatment modalities were collected and analyzed.