Protective effect of paeoniflorin on HO induced Schwann cells injury based on network pharmacology and experimental validation.

This study was to investigate the protective effect of paeoniflorin (PF) on hydrogen peroxide-induced injury. Firstly, "SMILES" of PF was searched in Pubchem and further was used for reverse molecular docking in Swiss Target Prediction database to obtain potential targets. Injury-related molecules were obtained from GeenCards database, and the predicted targets of PF for injury treatment were selected by Wayne diagram.

Improving the structural stability and electrochemical performance of NaLiTiO nanoparticles MgF coating.

To improve their electrochemical performance and structural stability, NaLiTiO (NLTO) nanoparticles were synthesized and then coated with a very thin MgF layer. Microscopy confirmed that the MgF-NLTO particles are about 150-250 nm in size, and that the thickness of the MgF layer for the MgF-NLTO-5 sample is ∼5 nm. Electrochemical measurements showed that the charge-discharge specific capacities of the five samples under a current density of 50 mA g after 100 cycles are 110.

Norcantharidin induces growth inhibition and apoptosis of glioma cells by blocking the Raf/MEK/ERK pathway.

Background: Malignant gliomas represent the most common primary brain tumors. The prognosis of patients with malignant gliomas is poor in spite of current intensive therapy and novel therapeutic modalities are needed. Here we report that norcantharidin is effective in growth inhibition of glioma cell lines in vitro.