Suppression of breast cancer cell growth by Her2-reduced AR serine 81 phosphorylation.

Breast cancer is a hormone-related carcinoma and the most commonly diagnosed malignancy in women. Although Her-2, estrogen receptor (ER), and progesterone receptor (PR) are the major diagnostic markers and therapeutic targets to breast cancer, searching for additional molecular targets remains an important issue and one of the candidates is androgen receptor (AR). AR has been shown expressed in 70% breast cancer patients and connects to low recurrence and high survival rate.

Diverse presentations in pediatric Meckel's diverticulum: a review of 100 cases.

Background: Our objective was to analyze demographics and characteristics of Meckel's diverticulum with different manifestations in pediatric patients.

Methods: This is a retrospective study in children with symptomatic Meckel's diverticulum who underwent resection between September 1998 and October 2010. The diagnosis was confirmed by surgery and pathology.