Static balance function in children with cochlear implants.

Objective: This study aimed to assess the static balance function in deaf adolescents with cochlear implants.

Methods: We included 24 adolescents who had received unilateral cochlear implantation for at least 5 years. Each subject underwent stabilometry testing under 4 different conditions: (A) firm surface with eyes open; (B) firm surface with eyes closed; (C) foam pad with eyes open; and (D) foam pad with eyes closed.

Assessing the development of balance function in children using stabilometry.

Objective: This study assessed the development of balance function in children using platform stabilometry.

Methods: A total of 251 healthy children aged from 3 to 12 years were enrolled in this study. Each subject underwent stabilometry under four various conditions (A: firm surface with eyes open; B: firm surface with eyes closed; C: foam pad with eyes open; and D: foam pad with eyes closed).

Myelination progression in language-correlated regions in brain of normal children determined by quantitative MRI assessment.

Objective: To investigate the myelination progression course in language-correlated regions of children with normal brain development by quantitative magnetic resonance imaging (MRI) analysis compared with histological studies.

Methods: The subjects were 241 neurologically intact neonates, infants and young children (128 boys and 113 girls) who underwent MRI between 2001 and 2007 at the University of Tokyo Hospital, ranging in age from 0 to 429 weeks corrected by postnatal age. To compare their data with adult values, 25 adolescents and adults (14 men and 11 women, aged from 14 to 83 years) were examined as controls.

Early myelination patterns in the central auditory pathway of the higher brain: MRI evaluation study.

Objective: The purpose of this study was to use magnetic resonance imaging (MRI) to investigate the early myelination patterns of the central auditory pathway and then compare the data with past histological research. We observe the MRI signal intensity of the central auditory pathway and clarify the time course difference between MRI and previous histological research studies.

Methods: A total of 192 infants ranging in age from -4 to 224 corrected postnatal weeks were included in the study.

Hearing profile and MRI myelination of auditory pathway in Pelizaeus-Merzbacher disease.

Conclusions: This study showed that delayed auditory pathway myelination is common in Pelizaeus-Merzbacher disease (PMD), but this delay does not necessarily indicate poor hearing function.

Objective: PMD is a rare recessively inherited X-linked leukodystrophy characterized by defective central nervous system myelination owing to a mutation in the proteolipid protein gene (PLP). The aims of this study were to evaluate the hearing function and auditory brain response (ABR) findings of patients with PMD and relate these findings to MRI-assessed myelination in the central auditory pathway.

Temporal bone pathological study on maxillary sinus carcinoma with bilateral temporal bone metastasis.

We report a case in which metastasis occurred from a left-side maxillary carcinoma to bilateral temporal bones through different routes, manifested by rapidly progressing left-side mixed hearing loss, left-side vestibular dysfunction, and serous otitis media. Later the left-side hearing threshold became severely elevated, suggesting profound sensory hearing loss. Histopathology of the temporal bones revealed that the side with the lesion was severely damaged by tumor through direct and hematogenous metastasis.

Early myelination patterns in the brainstem auditory nuclei and pathway: MRI evaluation study.

Objective: The purpose of this study is to investigate the early myelination patterns of brainstem auditory nuclei and pathway on magnetic resonance imaging compared with past histological research. We aimed to identify the time course difference in myelination of the brainstem auditory nuclei and pathway between magnetic resonance imaging and histological research results.

Methods: Subjects were 192 infants ranging in age from -4 to 224 corrected postnatal weeks.

Tuberculous meningitis-induced unilateral sensorineural hearing loss: a temporal bone study.

The relationship between meningitis and sensorineural hearing loss (SNHL) has long been studied. Many histopathological studies of animal models and human temporal bones with respect to bacterial meningitis have been carried out. However, the relationship between SNHL and tuberculous meningitis was seldom addressed and the pathophysiology remains unclear.