Publications by authors named "Chen-Chen Pan"
A study addressing the influence of type 2 diabetes on the prognosis of acute-on-chronic liver failure patients was reviewed. Some statistical deficiencies were found in the reviewed article, and the sample size was too small to support the study. In addition, age should have been considered as one of the prognostic factors.
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- Wolbachia is a type of bacteria that infects insects and affects their reproduction, primarily through a phenomenon called cytoplasmic incompatibility (CI), where uninfected eggs fail to develop when fertilized by infected sperm.
- The study used advanced metabolomics techniques to identify 414 metabolites whose levels changed due to Wolbachia infection in male flies, showing that the bacteria impact various metabolic pathways, including those related to energy and nutrient metabolism.
- Further analysis indicated that Wolbachia infection leads to increased energy use and oxidative stress in hosts, resulting in defects in sperm development and reduced egg hatch rates, highlighting the role of metabolism in paternal reproductive issues.