Enhancing prediction of parenchymal hemorrhage type 2 after endovascular treatment in acute ischemic stroke using dual-phase CTA.

Objective: To evaluate the effectiveness of dual-phase CT angiography (CTA) in predicting parenchymal hemorrhage type 2 (PH2) following endovascular thrombectomy (EVT) in patients with acute ischemic stroke (AIS).

Methods: A retrospective analysis was conducted across two centers, including 232 AIS patients who underwent EVT. Three predictive models were developed: a clinical model (Model C), a clinical model incorporating single-phase CTA data (Model CS), and a clinical model incorporating dual-phase CTA data (Model CD).

Associations Between Peer Relationships and Depressive Symptoms in Rural Children: Undirected and Bayesian Network Analyses.

Previous studies have noted links between peer relationships and depressive symptoms, but few have explored the subtle internal connections and inherent directionalities of these associations. Undirected and Bayesian network analyses were utilized to explore the interrelationships among key constructs in this study, which focused on 802 Chinese rural children (M= 12.16 years, SD = 0.

Effect of double-induced on whey protein isolate nanoparticle formation and stabilized food-grade Pickering emulsions: Stability and gastrointestinal digestion.

The effects of non-heat-induced and double-induced(heat-induced and Na-induced) whey protein isolate nanoparticles (WPINs) at concentrations of C = 1 %, 2 %, and 5 % as well as oil fractions (φ = 0.1, 0.4, and 0.

Network study of miRNA regulating traumatic heterotopic ossification.

Objective: Objective: To identify and analyze the microRNAs that are expressed differently (DE-miRNAs) and forecast their potential roles in the pathophysiological process of traumatic heterotopic ossification (THO).

Methods: We conducted RNA sequencing on six samples of normal bone and THO tissues from the patients and conducted differential expression analysis of miRNA. The biological activities of the target genes of the differentially expressed microRNAs (DE-miRNAs) were investigated using Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses.

Single-cell transcriptomes of dissecting the intra-tumoral heterogeneity of breast cancer microenvironment.

Objective: To investigate the mechanism by which heterogeneity in breast cancer developed and acted in single-cell transcriptomes.

Methods: The composition of breast cancer based on the single-cell transcriptomes of 54,055 high-quality cells from clinical specimens of 4 malignant and 4 non-malignant patients were investigated.

Results: We identified six common expression programs and six subtype-specific expression programs form malignant epithelial cells.

Effective targets of intervention on generalized anxiety symptoms across whole adolescence and emerging adulthood: network analysis and insilico intervention.

Early-onset generalized anxiety symptoms have severe impacts on youth development. Age differences in anxiety symptoms are obscure. Effective intervention targets need further investigation.

Disclosure to Whom Matters: Association Between Disclosure of Sexual Orientation and Mental Health Among Chinese LGB People.

Objective: This study aimed to explore the association between disclosure of one's sexual orientation in different social contexts and mental health outcomes among LGB individuals.

Methods: This study used a nationwide sample of 7867 LGB individuals in the mainland of China.

Results: Findings revealed that the disclosure process was associated with positive consequences in several specific contexts such as schools, workplaces, and close friendships, but not in the family context.

Understanding the Relationship Between Trait Mindfulness and Perceived Stress: The Serial Multiple Mediating Roles of Basic Psychological Needs Satisfaction and Psychological Flexibility.

Although research suggests that trait mindfulness has been negatively associated with perceived stress, an integrative examination of the underlying mechanisms is lacking. Consequently, the purpose of this study was to establish an integrative model within Monitor and Acceptance Theory (MAT). This model examined the relationship between trait mindfulness and perceived stress by assessing two important psychological resources: basic psychological needs satisfaction (BPNS) and psychological flexibility.

The Impression Management Consequences of Hiding Effort Among Adolescents: The Mediating Role of Authenticity.

Hiding effort has become prevalent among adolescents; however, whether this behavior benefits or harms their social impression remains unclear. The study explored whether hiding effort is an effective impression management strategy to obtain high popularity, likeability, interpersonal trust, and cooperation intention from peers. Using hypothetical scenarios, Study 1 ( = 243) found that hiding effort led to lower popularity, likeability, interpersonal trust, and cooperation intention among adolescents.

Similarities and differences in core symptoms of problematic smartphone use among Chinese students enrolled in grades 4 to 9: A large national cross-sectional study.

Children and adolescents are highly susceptible to problematic smartphone usage. We employed network analysis to explore the similarities and differences in the core symptoms of problematic smartphone use across grades 4-9, using a large nationwide sample. This study included 8552 children and adolescents (Mage = 12.

Bioinformatic analysis of hippocampal histopathology in Alzheimer's disease and the therapeutic effects of active components of traditional Chinese medicine.

Background And Aim: Pathological changes in the central nervous system (CNS) begin before the clinical symptoms of Alzheimer's Disease (AD) manifest, with the hippocampus being one of the first affected structures. Current treatments fail to alter AD progression. Traditional Chinese medicine (TCM) has shown potential in improving AD pathology through multi-target mechanisms.

Frontiers and hotspots evolution in mild cognitive impairment: a bibliometric analysis of from 2013 to 2023.

Background: Mild cognitive impairment is a heterogeneous syndrome. The heterogeneity of the syndrome and the absence of consensus limited the advancement of MCI. The purpose of our research is to create a visual framework of the last decade, highlight the hotspots of current research, and forecast the most fruitful avenues for future MCI research.

Attachment Style Modifies the Effect of Spousal Support on Postpartum Depression in Women.

Objective: This study aims to examine the impact of spousal support on postpartum depression in women with different attachment styles and assessing if attachment style influences this effect.

Methods: From March to May 2022, 96 couples with late-stage pregnant women were randomly selected from tertiary maternity hospitals in Shandong and Guangdong provinces for a prepartum survey. Psychological assessments were conducted using the Adult Attachment Scale, Dyadic Coping Inventory, and the Patient Health Questionnaire-9 (PHQ-9) Depression Scale.

Long-term path planning with optimal deployment of a charging station for monitoring photovoltaic solar farms.

Quadrotor technology has become increasingly important in the field of photovoltaic (PV) solar farm monitoring, but short battery life is one of the primary factors limiting its further application. To address above issue, this study proposes a linear temporal logic (LTL)-based path planning algorithm that considers the need for charging together with multiple visits to PV equipments, a single visit to communication equipment, and the avoidance of restricted regions, which enables the long-term monitoring of PV solar farms. Particularly, the location of a charging station can be determined optimally and efficiently by a heuristic algorithm based on the nonlinear programming and branch and bound (NLP-BB) algorithm.

Effects of Exocellobiohydrolase CBHA on Fermentation of Tobacco Leaves.

The quality of tobacco is directly affected by macromolecular content, fermentation is an effective method to improve biochemical properties. In this study, we utilized CBHA (cellobiohydrolase A) glycosylase, which was expressed by , as an additive for fermentation. The contents of main chemical components of tobacco leaves after fermentation were determined, and the changes of microbial community structure and abundance in tobacco leaves during fermentation were analyzed.

A simulation-based network analysis of intervention targets for adolescent depressive and anxiety symptoms.

Although previous research has well explored central and bridge symptoms of mental health problems, little examined whether these symptoms can serve as effective targets for intervention practices. Based on the Ising model, this study constructed a network structure of depressive and anxiety symptoms. The NodeIdentifyR algorithm (NIRA) was used to simulate interventions within this network, examining the effects of alleviating or aggravating specific symptoms on the network's sum scores.

No genetic link between Parkinson's disease and SARS-CoV-2 infection: a two-sample Mendelian randomization study.

Objective: Existing literature has not clearly elucidated whether SARS-CoV-2 infection increases the incidence of Parkinson's disease or if Parkinson's disease patients are more susceptible to the effects of SARS-CoV-2 infection. To clarify the issue, this study employs a genetic epidemiological approach to investigate the association.

Methods: This study utilizes a two-sample Mendelian randomization analysis.

Association between the atherogenic index of plasma and left ventricular hypertrophy in patients with obstructive sleep apnea: a retrospective cross-sectional study.

Background: The atherogenic index of plasma (AIP) is a simple and reliable marker of insulin resistance and is closely associated with various cardiovascular diseases (CVDs). However, the relationships between AIP and left ventricular (LV) geometric indicators have not been adequately assessed. This study was carried out to investigate the association between AIP and LV geometric abnormalities in obstructive sleep apnea (OSA) patients.

Dipolar Microenvironment Engineering Enabled by Electron Beam Irradiation for Boosting Catalytic Performance.

Creating a diverse dipolar microenvironment around the active site is of great significance for the targeted induction of intermediate behaviors to achieve complicated chemical transformations. Herein, an efficient and general strategy is reported to construct hypercross-linked polymers (HCPs) equipped with tunable dipolar microenvironments by knitting arene monomers together with dipolar functional groups into porous network skeletons. Benefiting from the electron beam irradiation modification technique, the catalytic sites are anchored in an efficient way in the vicinity of the microenvironment, which effectively facilitates the processing of the reactants delivered to the catalytic sites.