Publications by authors named "Chen You-Mei"
Pine wilt disease, caused by the pine wood nematode (PWN, ), is a major quarantine forest disease that poses a threat to various pine species, including (masson pine), worldwide. Breeding of PWN-resistant pine trees is an important approach to prevent the disease. To expedite the production of PWN-resistant accessions, we investigated the effects of maturation medium treatments on somatic embryo development, germination, survival, and rooting.
View Article and Find Full Text PDFGenetic Underpinnings and Audiological Characteristics in Children With Unilateral Sensorineural Hearing Loss.
Otolaryngol Head Neck Surg
November 2023
Article Synopsis
- * Researchers analyzed data from 38 children diagnosed with USNHL, finding genetic variants in about 21% of cases, particularly linked to specific genes like GJB2, PAX3, and EDNRB.
- * The findings suggest that genetic testing can help identify the causes and features of USNHL, which is important for effective diagnosis and treatment in affected children.
Background: Waardenburg syndrome (WS) is a hereditary, genetically heterogeneous disorder characterized by variable presentations of sensorineural hearing impairment and pigmentation anomalies. This study aimed to investigate the clinical features of WS in detail and determine the genetic causes of patients with clinically suspected WS.
Methods: A total of 24 patients from 21 Han-Taiwanese families were enrolled and underwent comprehensive physical and audiological examinations.
[Surveillance results of national monitoring sites for soil-transmitted nematode infections in Xinchang County from 2009 to 2017].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
May 2018
Objective: To understand the infection status of soil-transmitted nematodes in Xinchang County, so as to offer the evidence for the formulation of control measures.
Methods: The infection of soiltransmitted nematodes in residents was investigated by using the Kato-Katz method and cellophane anal swab.
Results: A total of 3 069 people were examined in 2009, 2012 and 2017, of which 1 520 people were male and 61 people were infected, with the infection rate of 4.
Identification of Glucose-responsive and Insulin-responsive Elements in Promoter of Mouse ob Gene.
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
January 2000
Article Synopsis
- Glucose and insulin were found to increase the expression of the leptin gene by targeting specific regions in its promoter region in both lab settings (in vitro) and living organisms (in vivo).
- Researchers conducted experiments on mouse fat cells to pinpoint the genetic elements influencing this effect, using techniques like Gel mobility shift assays (GMSA) and other assays to study DNA binding.
- They identified a new glucose-responsive element (GLRE) and insulin-responsive element (IRE) in a specific DNA sequence within the leptin gene promoter, suggesting that glucose and insulin enhance leptin expression by inhibiting the binding of a transcription factor to this region.