Lactic acid/tartaric acid-maltitol antibacterial activity against spoilage bacteria and prevention of yellowing and wilting in spinach and oilseed rape.

The wilting and yellowing of leafy vegetables caused by spoilage bacteria resulted in serious resource wastage. This study investigated the efficacy of a combined lactic acid (LA) and tartaric acid (TA) treatment against four predominant spoilage bacteria (Erwinia persicina, Citrobacter freundii, Pseudomonas putida, and Pseudomonas punonensis) isolated from spinach and oilseed rape. Detailed analysis using Fourier-transform infrared spectroscopy, flow cytometry, scanning electron microscopy, and light microscopy revealed substantial cellular damage in the bacteria treated by LA and TA, including loss of intracellular material, and collapse of cellular morphology, as well as effective biofilm removal.

Unraveling 3d Transition Metal (Ni, Co, Mn, Fe, Cr, V) Ions Migration in Layered Oxide Cathodes: A Pathway to Superior Li-Ion and Na-Ion Battery Cathodes.

Li-ion and Na-ion batteries are promising systems for powering electric vehicles and grid storage. Layered 3d transition metal oxides ATMO (A = Li, Na; TM = 3d transition metals; 0 < x ≤ 2) have drawn extensive attention as cathode materials due to their exceptional energy densities. However, they suffer from several technical challenges caused by crystal structure degradation associated with TM ions migration, such as poor cycling stability, inferior rate capability, significant voltage hysteresis, and serious voltage decay.

Sophaline B inhibits non-small cell lung cancer by activating NLRP3/caspase-1/GSDMD-dependent pyroptosis and PI3K/AKT/mTOR-mediated autophagy.

Sophaline B (SPB), extracted from the seeds of L., is a natural bioactive compound that effectively exerts antiviral activities against the hepatitis B virus. This is the first study to demonstrate that SPB exerts anti-tumor effects on NSCLC by inducing pyroptosis and autophagy.

Recent Advancements in the Synthesis of Functional Polyolefins by Non-Bridged Half-Titanocenes.

Polyolefins are used widely due to their benefits such as being lightweight, chemical inertness, low cost, tunable properties, and easy processability. However, their nonpolar nature significantly limits their high-end applications. The non-bridged half-titanocenes exhibit remarkable catalytic activities with good comonomer incorporations in the olefin polymerization.

Clozapine boosting N/Cl co-doped carbon skeleton synergistically optimizing NaV(PO) with superior performance and excellent thermal stability.

Nowadays, the limited electronic conductivity and structural deterioration during battery cycling have hindered the widespread application of NaV(PO) (NVP). In response to these challenges, we advocate for a technique involving the application of carbon modifications to NVP to enhance its suitability as cathode material. This work involves the synthesis of N/Cl co-modified in situ carbon coatings derived from clozapine (CZP) through a facile hydrothermal route.

Regulatory interactions between APOBEC3B N- and C-terminal domains.

APOBEC3B (A3B) is implicated in DNA mutations that facilitate tumor evolution. Although structures of its individual N- and C-terminal domains (NTD and CTD) have been resolved through X-ray crystallography, the full-length A3B (fl-A3B) structure remains elusive, limiting understanding of its dynamics and mechanisms. In particular, the APOBEC3B C-terminal domain (A3Bctd) active site is frequently closed in models and structures.

Global trends in machine learning applied to clinical research in liver cancer: Bibliometric and visualization analysis (2001-2024).

This study explores the intersection of liver cancer and machine learning through bibliometric analysis. The aim is to identify highly cited papers in the field and examine the current research landscape, highlighting emerging trends and key areas of focus in liver cancer and machine learning. By analyzing citation patterns, this study sheds light on the evolving role of machine learning in liver cancer research and its potential for future advancements.

Assessment of Age-Related Microstructure Changes in Thigh Skeletal Muscle Based on Neurite Orientation Dispersion and Density Imaging.

Background: Neurite orientation dispersion and density imaging (NODDI) could offer information about the morphological properties of tissue. Diffusion microstructure imaging has been widely used, but the applicability of NODDI in skeletal muscle imaging remains to be explored.

Purpose: To evaluate microstructure parameters variations in skeletal muscle as indicators of age-related changes.

Adenocarcinoma of the rete testis: clinicopathological study of 18 cases with emphasis on MET amplification and a review of the literature.

Background: Knowledge regarding adenocarcinoma of the rete testis (ACRT) is extremely limited due to its scarcity.

Methods And Results: This study enrolled 18 patients with ACRT from multiple institutions. Clinicopathological and immunohistochemical features were investigated, together with a comprehensive review of 95 previously reported cases.

Electronic asymmetry of lattice oxygen sites in ZnO promotes the photocatalytic oxidative coupling of methane.

Photocatalytic oxidative coupling of methane with oxygen is promising to obtain valuable muti-carbon products, yet suffering low reactivity. Here, we apply cerium modifications on zinc oxide-supported gold catalysts based on the electronic asymmetry design of lattice oxygen to improve the coupling activity. The methane conversion rate exceeds 16000 μmol g h with muti-carbon selectivity of 94.

Mechanisms of fibrinogen trans-activation of the EGFR/Ca2+ signaling axis to regulate mitochondrial transport and energy transfer and inhibit axonal regeneration following cerebral ischemia.

Ischemic stroke results in inhibition of axonal regeneration but the roles of fibrinogen (Fg) in neuronal signaling and energy crises in experimental stroke are under-investigated. We explored the mechanism of Fg modulation of axonal regeneration and neuronal energy crisis after cerebral ischemia using a permanent middle cerebral artery occlusion (MCAO) rat model and primary cortical neurons under low glucose-low oxygen. Behavioral tests assessed neurological deficits; immunofluorescence, immunohistochemistry, and Western-blot analyzed Fg and protein levels.

Heterojunction of Y-substituted NaV(PO)-NaYO accelerating kinetics with superior performance for full sodium-ion batteries.

The inherent poor ionic and electronic conductivity and relatively low capacity seriously limit the development of NaV(PO) (NVP). Currently, Y substitution is proposed for the first time and corresponding Y-doped NVP samples are successfully synthesized by traditional solid phase method. By replacing V (0.

A mobile miR160-triggered transcriptional axis controls root stem cell niche maintenance and regeneration in Arabidopsis.

In multicellular organisms, communication between cells is vital for their fate determination. In plants, the quiescent center (QC) signals to adjacent stem cells to maintain them undifferentiated. However, how surrounding stem cells instruct the QC remains poorly understood.

BES-Designer: A Web Tool to Design Guide RNAs for Base Editing to Simplify Library.

CRISPR/Cas base editors offer precise conversion of single nucleotides without inducing double-strand breaks. This technology finds extensive applications in gene therapy, gene function analysis, and other domains. However, a crucial challenge lies in selecting the appropriate guide RNAs (gRNAs) for base editing.

Sophflarines B-E, four distinctive matrine alkaloids from Sophora flavescens with potential neuroprotective activities.

The four matrine-derived alkaloids, namely sophflarines B-E (1-4), with distinct skeleton types, were isolated from Sophora flavescens. Compounds 1 and 2 possess rare 1-aza-11-oxatricyclo[5.3.

Wuzi Yanzong Decoction Ameliorates Oligoasthenozoospermia by Up-Regulating Methyltransferase and Increasing Spata, Bcl, and Pik3 Series Genes Methylation Level.

Wuzi Yanzong decoction (WZYZD) belongs to the traditional formula for treating male infertility caused by oligoasthenozoospermia (OLI). This research aims to elucidate the therapeutic substance basis and potential pharmacological mechanisms of WZYZD in treating OLI. A total of 52 chemical ingredients were identified from WZYZD.

The Efficacy and Safety of the Rhomboid Intercostal Block for Postoperative Analgesia in Chest Surgery and Breast Surgery: A Systemic Review and Meta-Analysis.

Background: Prior research has suggested that the rhomboid intercostal block (RIB) may contribute to postoperative analgesia after surgeries of the chest and breast.

Objective: To explore the effectiveness and safety of RIB for postoperative analgesia, as well as whether RIB is superior to other types of nerve blocks.

Study Design: A systematic review and meta-analysis.

Mapping the research of mitochondria and Parkinson's disease: a bibliometric analysis.

Background: Parkinson's disease (PD) is a chronic, progressive neurodegenerative disorder primarily affecting the elderly. Relevant studies suggest a significant connection between the mitochondria and PD. Publications exploring this connection have steadily increased in recent years.

Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization.

Background: Alcohol-associated liver disease (ALD) is one of the most common chronic liver diseases worldwide. Fetuin-A (FetA) is a plasma glycoprotein closely related to fat accumulation in the liver. However, the role of FetA in ALD remains unclear.