The gene expression and bioinformatic analysis of choline trimethylamine-lyase ) and its activating enzyme () for gut microbes and comparison with their TMA production levels.

Recent studies revealed that some intestinal microorganisms anaerobically convert choline to trimethylamine (TMA) by choline TMA-lyase (). TMA is further oxidized to trimethylamine--oxide (TMAO), by the liver enzyme flavin-dependent monooxygenase 3 (FMO3). TMA in the serum is correlated with the risk of cardiovascular disease and some other diseases in human.

EURO-MUSCULUS/USPRM basic scanning protocols revisited in children.

High-resolution ultrasound (US) has been widely used in the evaluation of adult musculoskeletal disorders with several established high-quality scanning protocols. Despite the fact that US use is even more advantageous in the pediatric population, normal sonographic images of the major joints are lacking in children. Due to the excessive amount of hyaline cartilage, the bony landmarks can hardly be recognized.

The combined influence of substrate elasticity and surface-grafted molecules on the ex vivo expansion of hematopoietic stem and progenitor cells.

Umbilical cord blood (UCB) is an attractive source of hematopoietic stem and progenitor cells (HSPCs) for transplantation. However, the low number of HSPCs from a single UCB donor limits the direct transplantation of UCB to patients. Because little is known about the effects of the physical microenvironment on HSPC expansion, we investigated the ex vivo expansion of HSPCs cultured on biomaterials with different elasticities and grafted with different nanosegments.

Mechanism for controlling the monomer-dimer conversion of SARS coronavirus main protease.

The Severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (M(pro)) cleaves two virion polyproteins (pp1a and pp1ab); this essential process represents an attractive target for the development of anti-SARS drugs. The functional unit of M(pro) is a homodimer and each subunit contains a His41/Cys145 catalytic dyad. Large amounts of biochemical and structural information are available on M(pro); nevertheless, the mechanism by which monomeric M(pro) is converted into a dimer during maturation still remains poorly understood.

The k partition-distance problem.

Many applications of data partitioning (clustering) have been well studied in bioinformatics. Consider, for instance, a set N of organisms (elements) based on DNA marker data. A partition divides all elements in N into two or more disjoint clusters that cover all elements, where a cluster contains a non-empty subset of N.

Hyperfine aperiodic optical superlattice optimized by iterative domino algorithm for phase-matching engineering.

We proposed and experimentally demonstrated the iterative domino algorithm to optimize optical superlattice with >10(5) unit blocks to achieve arbitrary target phase-matching power spectrum. This scheme can achieve unprecedented overall conversion efficiency and spectral fidelity with extremely high computation efficiency.

Effect of the surface density of nanosegments immobilized on culture dishes on ex vivo expansion of hematopoietic stem and progenitor cells from umbilical cord blood.

Umbilical cord blood (UCB) is an attractive source of hematopoietic stem and progenitor cells for hematopoietic stem cell (HSC) transplantation. However, the low number of HSCs obtainable from a single donor of UCB limits direct transplantation of UCB to the treatment of pediatric patients. In this study, we investigated the ex vivo expansion of HSCs cultured on biomaterials grafted with several nanosegments, i.

Resectoscopic treatment of ectopic pregnancy in previous cesarean delivery scar defect with vasopressin injection.

Objective: To describe resectoscopic treatment with vasopressin injection as an effective surgical intervention for ectopic pregnancy in previous cesarean delivery scar (PCDS) defect.

Design: Case report.

Setting: University hospital.

Abdominal wall endometriomas.

Objective: Abdominal wall endometriosis is rare, with an incidence of 0.03-0.47% following cesarean delivery.

Expression, purification and DNA-binding activity of tilapia muscle-specific transcription factor, MyoD, produced in Escherichia coli.

MyoD is one of several helix-loop-helix proteins regulating muscle-specific gene expression. Using a reverse transcription-polymerase chain reaction, 5'-rapid cDNA end amplification, and plaque hybridization, MyoD cDNA was cloned from the mRNA of tilapia dorsal skeletal muscle. The 1015 bp MyoD cDNA product contained an 846 bp open reading frame with flanking regions of 115 and 64 bp at the 5'- and 3'-ends, respectively.