Assessing resting-state brain functional connectivity in adolescents and young adults with narcolepsy using functional near-infrared spectroscopy.

This study aimed to elucidate the alterations in the prefrontal cortex's functional connectivity and network topology in narcolepsy patients using functional near-infrared spectroscopy (fNIRS). Twelve narcolepsy-diagnosed patients from Guangxi Zhuang Autonomous Region's People's Hospital Sleep Medicine Department and 11 matched healthy controls underwent resting fNIRS scans. Functional connectivity and graph theory analyses were employed to assess the prefrontal cortex network's properties and their correlation with clinical features.

Abnormal prefrontal functional network in adult obstructive sleep apnea: A resting-state fNIRS study.

To assess prefrontal brain network abnormality in adults with obstructive sleep apnea (OSA), resting-state functional near infrared spectroscopy (rs-fNIRS) was used to evaluate 52 subjects, including 27 with OSA and 25 healthy controls (HC). The study found that patients with OSA had a decreased connection edge number, particularly in the connection between the right medial frontal cortex (MFG-R) and other right-hemisphere regions. Graph-based analysis also revealed that patients with OSA had a lower global efficiency, local efficiency, and clustering coefficient than the HC group.

Advances in diagnosing mild cognitive impairment and Alzheimer's disease using C-PIB- PET/CT and common neuropsychological tests.

Alzheimer's disease (AD) is a critical health issue worldwide that has a negative impact on patients' quality of life, as well as on caregivers, society, and the environment. Positron emission tomography (PET)/computed tomography (CT) and neuropsychological scales can be used to identify AD and mild cognitive impairment (MCI) early, provide a differential diagnosis, and offer early therapies to impede the course of the illness. However, there are few reports of large-scale C-PIB-PET/CT investigations that focus on the pathology of AD and MCI.

A Preliminary Study on Sympathetic Skin Response in Acute Ischemic Cerebrovascular Disease.

Purpose: The study aims to identify the characteristics of SSR in patients with AICVD and their correlation with clinical presentations.

Methods: SSR of the upper limbs, the National Institute of Health stroke scale (NIHSS), the Barthel index (BI), the Essen stroke risk score (ESRS), and imaging examinations, was evaluated in 30 healthy subjects and 66 patients with AICVD. All results were recorded and analyzed via Statistical Package for the Social Sciences (SPSS 22.

Helsmoortel-van der Aa syndrome in a Chinese pediatric patient due to nonsense mutation: A case report.

Background: Helsmoortel-van der Aa syndrome, also known as syndrome, is a condition that causes developmental delay, language impairment, autism spectrum, and variable extraneurologic features. It is caused by heterozygous mutations in the gene on chromosome 20q13. Most of the genetic causes of Helsmoortel-van der Aa syndrome have been reported are as nonsense or frameshift stop mutations in exon 5 of gene, while fewer truncating variants were discovered in exons 4 and the 5' end of exon 5.

Early Spontaneous Abortion in Fresh- and Frozen-Embryo Transfers: An Analysis of Over 35,000 Transfer Cycles.

Background: The aim of this study was to explore the risk factors for early spontaneous abortion (ESA) in fresh- and frozen-embryo transfers.

Methods: This retrospective cohort study comprised a total of 35,076 patients, including 15,557 women in the fresh-embryo transfer group and 19,519 women in the frozen-embryo transfer group from January 2016 to December 2020. The primary outcome of this study was ESA, which we defined as the termination of embryonic development before 12 weeks of pregnancy (i.

Impact of growth hormone supplementation on improving oocyte competence in unexplained poor embryonic development patients of various ages.

Objectives: To evaluate the effectiveness of Growth hormone (GH) co-treatment during fertilization (IVF) cycles in women of different ages who manifest unexplained poor embryonic development.

Method: This cohort study included a total of 2647 patients with unexplained poor embryonic development in their previous IVF procedures: 872 women received GH co-treatment and 1775 untreated women served as a control group. Patients were divided into 6 groups according to treatment and stratified by age (<35 years of age, A-GH group and A-control group; 35-40 years, B-GH group and B-control group; and ≥40 years, C-GH group and C-control group).

A simple nomogram prediction model to identify relatively young patients with mild cognitive impairment who may progress to Alzheimer's disease.

Aim: Construct a clinical predictive model based on easily accessible clinical features and imaging data to identify patients 65 years of age and younger with mild cognitive impairment(MCI) who may progress to Alzheimer's disease(AD).

Methods: From the ADNI database, patients with MCI who were less than or equal to 65 years of age and who had been followed for 6-60 months were selected.We collected demographic data, neuropsychological test scale scores, and structural magnetic images of these patients.

Four new species of (Gesneriaceae) in Yunnan province, China.

Four new species of (Gesneriaceae) are described and illustrated. These new species grow in pairs in montane forests in Yunnan province, China. One pair grows in Wenshan county, Southeast Yunnan, viz.

Two new taxa of Gesneriaceae in the karst regions in North Vietnam.

One new species and one new variety of Gesneriaceae in Vietnam are described, viz. Paraboea sinensis var. glabrissima and These two new taxa grow in limestone regions in North Vietnam.

Two new species of (Gesneriaceae) in forests in Southwest China, with compound and simple dichasia, respectively.

Two new species of Gesneriaceae, and are described and illustrated with photos. They grow in the forests from Yunnan Province of China. is closely related to (Hand.

, a new species of Gesneriaceae in Yunnan, China.

A new species of (Gesneriaceae) from Yunnan, China, W.H.Chen & Y.

Two new species of (Gesneriaceae) from the karst regions in Yunnan, China.

W.T.Wang in Gesneriaceae was described in 1983 and is characterized by its 4-lobed adaxial lip and undivided abaxial lip with acute apex.

Reassessment of Oliver (Gesneriaceae) based on molecular and palynological evidence.

The former genus is endemic to China, including two species, has been under consideration for incorporation into the expanded genus s.l. in Gesneriaceae.

Gesneriaceae in China and Vietnam: Perfection of taxonomy based on comprehensive morphological and molecular evidence.

No.

The extract of aquatic macrophyte Carex cinerascens induced colony formation in bloom-forming cyanobacterium Microcystis aeruginosa.

Colony formation in Microcystis aeruginosa played important roles in blooms formation. To study the effects of plant allelopathy on colony formation in M. aruginosa, unicellular M.

Seven new species of (Begoniaceae) in Northern Vietnam and Southern China.

Since 2016, KIB (Kunming Institute of Botany) and CPC (Centre for Plant Conservation of Vietnam) have conducted several surveys in the transboundary karst regions in Northern Vietnam and Southern China and seven new species in the genus Linn. (Begoniaceae) are firstly described. Amongst them, two species, Y.

Rediscovery and amended descriptions of (Begoniaceae) from North Myanmar.

Tebbitt was rediscovered in 2014 from Myanmar after 67 years based on its last collection in 1937. Its previously unknown female flower and inaccurate morphology of leaf and ovary have been additionally described. This species belongs to Begonia sect.

Mild encephalopathy/encephalitis with a reversible splenial lesion (MERS): A report of five neonatal cases.

Mild encephalopathy/encephalitis with a reversible splenial (MERS) lesion is a clinic-radiological entity. The clinical features of MERS in neonates are still not systemically reported. This paper presents five cases of MERS, and the up-to-date reviews of previously reported cases were collected and analyzed in the literature.

DNA transducer-triggered signal switch for visual colorimetric bioanalysis.

A simple and versatile colorimetric biosensor has been developed for sensitive and specific detection of a wide range of biomolecules, such as oligonucleotides and aptamer-recognized targets. Combining the signal transducer and catalyzed hairpin assembly (CHA)-based signal amplification, the target DNA binds with the hairpin DNA to form a new nucleic acid sequence and creates a toehold in the transducer for initiating the recycle amplification reaction of CHA. The catalyzed assembly process produces a large amount of G-rich DNA.

Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation.

Background: Proper functional association between mural cells and endothelial cells (EC) causes EC of blood vessels to become quiescent. Mural cells on tumor vessels exhibit decreased attachment to EC, which allows vessels to be unstable and proliferative. The mechanisms by which tumors prevent proper association between mural cells and EC are not well understood.

A simple electrochemical biosensor for highly sensitive and specific detection of microRNA based on mismatched catalytic hairpin assembly.

MicroRNAs (miRNAs) play vital regulatory roles in cancer development and a variety of diseases, which make them become promising biomarkers. Here, a simple electrochemical biosensor was developed for highly sensitive and specific detection of target miRNA using mismatched catalytic hairpin assembly (CHA). The target miRNA triggered the toehold strand displacement assembly of two hairpin substrates, which led to the cyclic reuse of the target miRNA and the CHA products.

Taxonomic status, phylogenetic affinities and genetic diversity of a presumed extinct genus, Paraisometrum W.T. Wang (gesneriaceae) from the karst regions of Southwest China.

Background: The karst regions in South China have an abundance of endemic plants that face high extinction risks. The Chinese Gesneriaceae endemic Paraisometrum mileense ( = Oreocharis mileensis), was presumed extinct for 100 years. After its re-discovery, the species has become one of five key plants selected by the Chinese forestry government to establish a new conservation category for plants with extremely small populations.