Geometric deep learning with adaptive full-band spatial diffusion for accurate, efficient, and robust cortical parcellation.

Cortical parcellation delineates the cerebral cortex into distinct regions according to their distinctiveness in anatomy and/or function, which is a fundamental preprocess in brain cortex analysis and can influence the accuracy and specificity of subsequent neuroscientific research and clinical diagnosis. Conventional methods for cortical parcellation involve spherical mapping and multiple morphological feature computation, which are time-consuming and prone to error due to the spherical mapping process. Recent geometric learning approaches have attempted to automate this process by replacing the registration-based parcellation with deep learning-based methods.

Correction of Non-Uniform Rotational Distortion in the Proximally Controlled Endoscopic OCTA.

Endoscopic Optical Coherence Tomography (OCT) can provide high-resolution cross-sectional images for internal organ tissues. Combining the endoscopic imaging with Optical Coherence Tomography Angiography (OCTA), information of blood vessels in superficial lumen tissues is expected to be acquired. However, in endoscopic OCT systems using proximal scanning probes, performance of OCTA encounters significant challenges due to non-uniform rotational distortion (NURD) caused by the non-constant rotation of the distal imaging unit.

 (Dothideomycetes, Ascomycota) species associated with Chinese spp.

This study is based on three terrestrial saprobic fungi associated with in Guangdong and Yunnan provinces in China. All isolated species matched with generic concepts of . Detailed morphological characteristics and combined multigene phylogeny of LSU, SSU, and TEF revealed that the new isolates represent two new species ( and ), and one new host and geographical record ().

Contrast-enhanced near-infrared photoacoustic microscopy and optical coherence tomography imaging of rat fundus.

In this paper, we design a multimodal visible/near-infrared photoacoustic microscopy and optical coherence tomography (VIS/NIR-PAM-OCT) system for imaging both retina and retinal pigment epithelium (RPE)/choroid complex layer. F127 and DSPE-PEG-cRGD encapsulated IR-1048 nanoparticles (FINPs) exhibiting absorption peak up to 1,064 nm were utilized as contrast agents to enhance NIR-PAM for imaging of fundus tissues. The fundus structure and vessels are clearly visualized by the multimodal imaging, and their parameters were quantitatively analyzed.

Intramedullary spinal cord abscess due to disseminated hypermucoviscous infection: A rare case report.

Background: Intramedullary spinal cord abscess (ISCA) is a rare and serious condition with high disability and mortality rates. is known for its aggressive and disseminated abscess formation. However, ISCA caused by has only been reported in two cases.

Key point of desert riparian forest development in the arid area: The response of phreatic water table depth to ecological water supply.

Desert riparian forest vegetation maintains the fragile balance of ecosystems in extreme arid areas. Raising the phreatic water table through efficient ecological water supply is the key to the desert riparian forests in extreme arid areas. The main objective of this study is to explore an innovative framework in which the response of phreatic water table depth (PWTD) to ecological water supply flow (EWSF) can be effectively reflected.

Endoscopic OCTA in continuous rotation and retraction scheme using a proximal scanning catheter.

Endoscopic optical coherence tomography (OCT) is widely used in the detection of morphological alterations in luminal organs, which provides high-resolution, three-dimensional (3D) images of internal tissues. In most cases, lesions are revealed early by microvascular pathological changes in cavity tissues. There is a significant demand for the performance of endoscopic OCT angiography (OCTA) to visualize the superficial capillaries.

Astral-DIA proteomics: Identification of differential proteins in sheep, goat, and cow milk.

Dairy products are of great benefit to human health, and the nutritional differences between different dairy products have attracted attention. In this study, DIA proteomics technique, combined with parallel reaction monitoring (PRM) as a validation method, was used for the qualitative and quantitative analysis of proteins in sheep, goat, and cow milk. In total, 4316 proteins were identified.

12-HETE/GPR31 induces endothelial dysfunction in diabetic retinopathy.

12-hydroxyeicosatetraenoic acid (12-HETE), a major metabolite of arachidonic acid, is converted by 12/15-lipoxygenase and implicated in diabetic retinopathy (DR). Our previous study demonstrated a positive correlation between 12-HETE and the prevalence of DR. However, reasons for the increased production of 12-HETE are unclear, and the underlying mechanisms through which 12-HETE promotes DR are unknown.

Experiences and needs of family members following sudden cardiac death: A meta-synthesis.

Objective: This meta-synthesis of qualitative studies aimed to explore the experiences and needs of family members of victims of sudden cardiac death.

Design: A meta-synthesis was conducted.

Data Sources: Five databases (PubMed, CINAHL, EMBASE, Web of Science, and China National Knowledge Infrastructure) were searched from establishment to May 2024.

Multi-objective double layer water optimal allocation and scheduling framework combing the integrated surface water - groundwater model.

Balancing the water consumption of agricultural and ecological is the key point of sustainable social and economic development in an inland river basin. The growth of desert riparian forests in inland river basins mainly depends on a certain phreatic water table depth (PWTD). The main object of this study was to allocate and schedule water resources to regulate the PWTD and satisfy agricultural water demand.

A Multi-Center, Multi-Parametric MRI Dataset of Primary and Secondary Brain Tumors.

Brain metastases (BMs) and high-grade gliomas (HGGs) are the most common and aggressive types of malignant brain tumors in adults, with often poor prognosis and short survival. As their clinical symptoms and image appearances on conventional magnetic resonance imaging (MRI) can be astonishingly similar, their accurate differentiation based solely on clinical and radiological information can be very challenging, particularly for "cancer of unknown primary", where no systemic malignancy is known or found. Non-invasive multiparametric MRI and radiomics offer the potential to identify these distinct biological properties, aiding in the characterization and differentiation of HGGs and BMs.

Label-free-based proteomics analysis reveals differential proteins of sheep, goat, and cow milk.

Regarding the limited information on species protein differences between sheep, goat, and cow milk, we analyzed the differentially expressed proteins in sheep, goat, and cow milk and their functional differences using label-free proteomics technology to identify potential biomarkers. In all, 770 proteins and 2,914 peptide segments were identified. Statistical analysis showed significant differences in the relative abundances of the 74 proteins among sheep, goat, and cow milk.

Dynamic changes of gut microbiota in mouse models of metabolic dysfunction-associated steatohepatitis and its transition to hepatocellular carcinoma.

Dysbiosis of gut microbiota may account for pathobiology in simple fatty liver (SFL), metabolic dysfunction-associated steatohepatitis (MASH), fibrotic progression, and transformation to MASH-associated hepatocellular carcinoma (MASH-HCC). The aim of the present study is to investigate gut dysbiosis in this progression. Fecal microbial rRNA-16S sequencing, absolute quantification, histopathologic, and biochemical tests were performed in mice fed high fat/calorie diet plus high fructose and glucose in drinking water (HFCD-HF/G) or control diet (CD) for 2, 16 weeks, or 14 months.

Sensitivity and stability improvement on slippery surface-aggregated substrate for trace heavy metals detection using NELIBS.

The sensitive and stable detection of trace heavy metals in liquid is crucial given its profound impact on various aspects of human life. Currently, nanoparticle-enhanced laser-induced breakdown spectroscopy (NELIBS) with dried droplet method (DDM) is widely applied for heavy metals detection. Nevertheless, the coffee ring effect (CRE) in DDM affects the stability, accuracy, and sensitivity of NELIBS.

Melatonin antagonizes oxidative stress-induced apoptosis in retinal ganglion cells through activating the thioredoxin-1 pathway.

This study aimed to explore the role of melatonin in oxidative stress-induced injury on retinal ganglion cells and the underlying mechanisms. The immortalized RGC-5 cells were treated with HO to induce oxidative injury. Cell viability was measured by Cell Counting Kit-8, and apoptosis was determined by flow cytometry and western blot assays.

Mechanisms by which sheep milk consumption ameliorates insulin resistance in high-fat diet-fed mice.

Sheep milk is rich in fat, protein, vitamins and minerals and is also one of the most important sources of natural bioactives. Several biopeptides in sheep milk have been reported to possess antibacterial, antiviral and anti-inflammatory properties, and they may prevent type 2 diabetes (T2D), disease and cancer. However, the precise mechanism(s) underlying the protective role of sheep milk against T2D development remains unclear.

Identification of pv. in Black Fungus and Efficient Recognition of Bongkrekic Acid and Toxoflavin Producing Phenotype by Back Propagation Neural Network.

pv. is a serious safety issue in black fungus due to the deadly toxin, bongkrekic acid. This has triggered the demand for an efficient toxigenic phenotype recognition method.

Triglyceride-glucose index as a valuable predictor for aged 65-years and above in critical delirium patients: evidence from a multi-center study.

Background: The triglyceride-glucose index (TyG), an established indicator of insulin resistance, is closely correlated with the prognosis of several metabolic disorders. This study aims to investigate the association between the TyG index and the incidence of critical delirium in patients aged 65 years and older.

Methods: We focused on evaluating patients aged 65 years and older diagnosed with critical delirium.

Adipose‑derived stem cell‑mediated alphastatin targeting delivery system inhibits angiogenesis and tumor growth in glioma.

Malignant glioma is a highly vascularized tumor. Therefore, inhibition of angiogenesis is an effective treatment strategy for it. Alphastatin is a 24‑amino acid peptide that has been demonstrated to inhibit glioma angiogenesis and tumor growth.

Coffee-Associated Endophytes: Plant Growth Promotion and Crop Protection.

Endophytic microbes are a ubiquitous group of plant-associated communities that colonize the intercellular or intracellular host tissues while providing numerous beneficial effects to the plants. All the plant species are thought to be associated with endophytes, majorly constituted with bacteria and fungi. During the last two decades, there has been a considerable movement toward the study of endophytes associated with coffee plants.

Metabolome Sequencing Reveals that Protein Arginine-N-Methyltransferase 1 Promotes the Progression of Invasive Micropapillary Carcinoma of the Breast and Predicts a Poor Prognosis.

Invasive micropapillary carcinoma (IMPC) of the breast is a special histopathologic type of cancer with a high recurrence rate and the biological features of invasion and metastasis. Previous spatial transcriptome studies indicated extensive metabolic reprogramming in IMPC, which contributes to tumor cell heterogeneity. However, the impact of metabolome alterations on IMPC biological behavior is unclear.