The rhythm gene (Brain and Muscle ARNT-Like 1) may play an important role in glioma tolerance for anti-angiogenesis therapy. In humans with glioma of different pathological grades, expression was significantly different, and the expression of (Angiopoietin 2) and (Vascular endothelial growth factor) was positively correlated with the expression of . Additionally, expression is positively correlated with the microvascular density and peritumoral edema of glioma.
View Article and Find Full Text PDFJ Neurol Surg A Cent Eur Neurosurg
July 2016
Background Hemifacial spasm (HFS) is generally treated by microvascular decompression (MVD). Inadequate separation of vessel and nerve or adhesive inflammation surrounding the nerve root may cause recurrence. Objective To explore a method to reduce the incidence of adhesions and to ensure sufficient separation of the offending vessel and nerve during MVD.
View Article and Find Full Text PDFGrowing evidence shows that deregulation of the circadian clock plays an important role in the development of malignant tumors, including gliomas. However, the molecular mechanisms of gene chnages controlling circadian rhythm in glioma cells have not been explored. Using real time polymerase chain reaction and immunohistochemistry techniques, we examined the expression of two important clock genes, cry1 and cry2, in 69 gliomas.
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