A Regulatory Network Contributing to Breast Cancer.

Background: Translocase of inner mitochondrial membrane 17A () is overexpressed in breast cancer (BRCA), and upregulation can increase the aggressiveness of BRCA cells. This study examined the influence of the gene network on BRCA outcome.

Methods: Expression levels of were compared between normal and tumor tissues from the Oncomine database, and the association with patient survival was analyzed using Kaplan-Meier Plotter.

High Sensitivity Plasmonic Sensor Based on Fano Resonance with Inverted U-Shaped Resonator.

Herein, we propose a tunable plasmonic sensor with Fano resonators in an inverted U-shaped resonator. By manipulating the sharp asymmetric Fano resonance peaks, a high-sensitivity refractive index sensor can be realized. Using the multimode interference coupled-mode theory and the finite element method, we numerically simulate the influences of geometrical parameters on the plasmonic sensor.

An Integrated Detection Based on a Multi-Parameter Plasmonic Optical Fiber Sensor.

In this paper, a multi-parameter integrated detection photonic crystal fiber (PCF) sensor based on surface plasmon resonance (SPR) is proposed for its application in detecting temperature, magnetic field, and refractive index. The air holes on both sides of the fiber core were coated with gold film and introduced to the temperature-sensitive medium (PDMS) and magnetic fluid (MF), detecting temperature and magnetic field, respectively. The graphene layer is also presented on the gold film of the D-type side polished surface to improve the sensor sensitivity.

Path following identification of unmanned aerial vehicles for navigation spoofing and its application.

As unmanned aerial vehicles (UAVs) use global navigation satellite systems for positioning, the openness and weak security of satellite navigation signals make these systems easily falsifiable. By leveraging these characteristics, we propose a path following identification algorithm to gain control of UAVs using navigation spoofing as a countermeasure against illegal activities. Our contribution is threefold.

Investigation of Anisotropic Subsequent Yield Behavior for 45 Steel by the Distortional Yield Surface Constitutive Model.

The subsequent anisotropic yield behavior of 45 steel was predicted by the distortional yield surface constitutive model, which can describe the anisotropic subsequent yield and the cross effect of metal associating with loading history. The yield characteristics and plastic hardening behaviors of the 45 steel were simulated under three preloading paths including pre-torsion, pre-tension, and pre-tension-torsion. Based on the comparison between the experimental yield stresses and the simulation by the classical Chaboche model, the proposed model can describe the remarkable anisotropic yield behavior related to the loading history, which can effectively describe the sharp point of yield surface in pre-loading direction and the smaller curvature near its opposite direction.

Improved MAC layer protocol of Wifi for satellite network.

With the development and universal application of satellite technology, an important way to expand the function of satellites is setting up inter-satellite networks to make them work together. Traditional satellite networking methods generally adopt a fixed time slot allocation method, which is not suitable for small satellite groups with low latency and high throughput requirements. In order to solve this problem, it has been proposed to apply the traditional Wifi protocol in satellite networking.

The Anisotropic Distortional Yield Surface Constitutive Model Based on the Chaboche Cyclic Plastic Model.

Considering the cross effect in the evolution of subsequent yield surfaces for metals, an anisotropic distortional yield surface constitutive model is developed. By introducing an anisotropic distortional hardening function into the isotropic hardening part of the classical Chaboche rate-dependent constitutive model, the plastic-deformation-induced distortional and anisotropic hardening behaviors of subsequent yield surfaces are characterized. The experimental data of distortional yield surfaces for T2 pure copper under three different loading paths, including pre-tension, pre-torsion, and pre-tension-torsion proportional loading of 45-degree, are simulated by implementing the models into a numerical user defined material (UMAT) procedure based on the ABAQUS finite element package.

Identification of methylation sites and signature genes with prognostic value for luminal breast cancer.

Background: Robust and precise molecular prognostic predictors for luminal breast cancer are required. This study aimed to identify key methylation sites in luminal breast cancer, as well as precise molecular tools for predicting prognosis.

Methods: We compared methylation levels of normal and luminal breast cancer samples from The Cancer Genome Atlas dataset.

Analysis of the miRNA-mRNA-lncRNA network in human estrogen receptor-positive and estrogen receptor-negative breast cancer based on TCGA data.

Estrogen receptor-positive (ER) and ER-negative (ER) subtypes of breast cancer have distinct clinical outcomes because they respond differentially to endocrine therapies. We aimed to comprehensively analyze differentially expressed microRNA (miRNAs), long non-coding RNAs (lncRNAs) and mRNAs in different ER subtypes as well as to identify prognosis-related RNAs. The expression levels of miRNAs, lncRNAs, and mRNAs between breast cancer and normal samples were compared using data from The Cancer Genome Atlas database.

Uplink Scheduling of Navigation Constellation Based on Immune Genetic Algorithm.

The uplink of navigation data as satellite ephemeris is a complex satellite range scheduling problem. Large-scale optimal problems cannot be tackled using traditional heuristic methods, and the efficiency of standard genetic algorithm is unsatisfactory. We propose a multi-objective immune genetic algorithm (IGA) for uplink scheduling of navigation constellation.

The Availability of Space Service for Inter-Satellite Links in Navigation Constellations.

Global navigation satellite systems (GNSS) are widely used in low Earth orbit (LEO) satellite navigation; however, their availability is poor for users in medium Earth orbits (MEO), and high Earth orbits (HEO). With the increasing demand for navigation from MEO and HEO users, the inadequate coverage of GNSS has emerged. Inter-satellite links (ISLs) are used for ranging and communication between navigation satellites and can also serve space users that are outside the navigation constellation.

Correlational study on mitochondrial DNA mutations as potential risk factors in breast cancer.

The presented study performed an mtDNA genome-wide association analysis to screen the peripheral blood of breast cancer patients for high-risk germline mutations. Unlike previous studies, which have used breast tissue in analyzing somatic mutations, we looked for germline mutations in our study, since they are better predictors of breast cancer in high-risk groups, facilitate early, non-invasive diagnoses of breast cancer and may provide a broader spectrum of therapeutic options. The data comprised 22 samples of healthy group and 83 samples from breast cancer patients.

Serum cytokine profile in patients with breast cancer.

Breast cancer is the leading cause of cancer-related death among women, with a more 20% 5-year survival rate after metastases. It is therefore critical to improve early diagnosis in order to improve disease prognosis. This study investigates cytokine profiles of breast cancer serum with the aim of identifying biomarkers for early diagnosis.

Study on the constitutive model for jointed rock mass.

A new elasto-plastic constitutive model for jointed rock mass, which can consider the persistence ratio in different visual angle and anisotropic increase of plastic strain, is proposed. The proposed the yield strength criterion, which is anisotropic, is not only related to friction angle and cohesion of jointed rock masses at the visual angle but also related to the intersection angle between the visual angle and the directions of the principal stresses. Some numerical examples are given to analyze and verify the proposed constitutive model.

[Changes of microRNA expression profiles in Vero cells induced by HSV-2 LAT overexpression].

Objective: To investigate the changes in the microRNA expression profile of Vero cells induced by HSV-2 LAT overexpression.

Methods: The full-length open reading frame of HSV-2 LAT was synthesized and cloned into pRetroQ- AcGFP1-C1 vector, and the recombinant retrovirus expressing HSV-2 LAT was packaged. Using a microRNA microarray, the microRNA expression profile changes in Vero cells were analyzed after infection with the recombinant retrovirus.

Real-time digital compensation to reduce acceleration's sensitivity in quartz resonator.

The paper presents a digital compensator imposing real-time voltage to compensate the frequency offset of quartz resonator under acceleration. To begin with, a triple-axis MEMS acceleration sensor, whose package is less than 3 mm × 3 mm × 0.9 mm, is mounted at the bottom of quartz resonator.

[Preparation of a monoclonal antibody against fusion protein preM/EIII of WNV].

Objective: To prepare a monoclonal antibody (mAb) against the fusion protein preM/EIII of West Nile virus (WNV) for clinical detection of WNV.

Methods: Sp2/0 cells were fused with the spleen cells of BALB/c mice immunized with the recombinant fusion protein preM/EIII expressed in E. coil to obtain the hybridoma cell line that secreted preM/EIII mAb.

[The use of kidney-shaped pressure bandage to prevent postoperative salivary fistula].

Purpose: To evaluate the usefulness of pressure bandage with kidney-shaped cotton pad in parotidectomy and the relevant factors of parotid salivary fistula occurring after parotidectomy.

Methods: One hundred and ninety-six patients with parotid benign tumor or tumor-like lesions were randomly divided into two groups, 100 cases in the kidney-shaped cotton pad group and 96 cases in the traditional management group. The incidence of postoperative salivary in relation to surgical procedure, main parotid duct ligation, and parotid salivary fistula was analyzed.