RAS, a Pentatricopeptide Repeat Protein, Interacts with OsTRX z to Regulate Chloroplast Gene Transcription and RNA Processing.

Thioredoxin z (TRX z) plays a significant role in chloroplast development by regulating the transcription of chloroplast genes. In this study, we identified a pentatricopeptide repeat (PPR) protein, rice albino seedling-lethal (RAS), that interacts with OsTRX z. This interaction was initially discovered by using a yeast two-hybrid (Y2H) screening technique and was further validated through Y2H and bimolecular fluorescence complementation (BiFC) experiments.

Versatile and robust transparent polymer film with preprogrammed diffusion and bidirectional irreversible fluorescence for sequential information encryption.

The materials currently available for information encryption often suffer from low transparency, poor mechanical strength, and a reliance on single decryption conditions, which limits their security and hence application potential. To address these challenges, we developed a transparent, mechanically robust polymer film inspired by the camouflage and communication strategies of the glass squid. In this film, 2,5-dihydroxyterephthalic acid (DHTA) and zinc acetate dihydrate are integrated into a crosslinked polyvinyl alcohol-glutaraldehyde (PVA-GA) matrix to achieve bidirectional irreversible fluorescence and sequential decryption.

Cu-EAB zeolite catalyst: A promising candidate with excellent SO poisoning resistance for NH-SCR reaction.

In this work, we synthesized Cu-EAB catalysts with an EAB topology for the NH-SCR of NO and evaluated their resistance to SO poisoning for the first time. The Cu-EAB catalyst showed superior NO conversion and selectivity for N, along with a notable tolerance to high space velocities and SO, outperforming the commercial Cu-CHA catalyst. This enhanced resistance was attributed to the Cu species formation at the 2.

Copper-Copper Oxide Heterostructural Nanocrystals Anchored on g-CN Nanosheets for Efficient Visible-Light-Driven Photo-Fenton-like Catalysis.

The development of efficient and sustainable photocatalysts for wastewater treatment remains a critical challenge in environmental remediation. In this study, a ternary photocatalyst, Cu-CuO/g-CN, was synthesized by embedding copper-copper oxide heterostructural nanocrystals onto g-CN nanosheets via a simple deposition method. Structural and optical characterization confirmed the successful formation of the heterostructure, which combines the narrow bandgap of CuO, the high stability of g-CN, and the surface plasmon resonance (SPR) effect of Cu nanoparticles.

Diversity of primary vegetation species of lake shore impacts largely carbon emissions in thermokarst lakes on the Qinghai-Tibet plateau.

Terrestrial organic matter from surrounding primary vegetation is critical for carbon cycling in thermokarst lakes. However, the characteristics and contribution of this vegetation in shaping microbial community and affecting carbon emissions in thermokarst lakes remain poorly understood. This study quantifies the influence of lakeshore primary vegetation characteristics on microbial community and carbon emissions across lakes with different vegetation types on the Qinghai-Tibet Plateau (QTP).

Activation of IP10/CXCR3 Signaling is Highly Coincidental with PrP Deposition in the Brains of Scrapie-Infected Mice.

Objective: To analyze the relationship between Chemokine IP10 and its receptor CXCR3 during prion infection.

Methods: We investigated the increases in IP10 signals, primarily localized in neurons within the brains of scrapie-infected mice, using western blotting, ELISA, co-immunoprecipitation, immunohistochemistry, immunofluorescence assays, and RT-PCR.

Results: Both CXCR3 levels and activation were significantly higher in the brains of scrapie-infected mice and prion-infected SMB-S15 cells.

Domain generalization for mammographic image analysis with contrastive learning.

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse styles and qualities. The diversity of data often comes from the use of various scanners of vendors.

An early warning model for predicting major adverse kidney events within 30 days in acute pancreatitis patients.

Background: Renal impairment is a common outcome of acute pancreatitis. Nevertheless, research on predictive models for major adverse kidney events within 30 days (MAKE30) in acute pancreatitis (AP) has been scarce.

Methods: A retrospective study was conducted at Gansu Provincial Hospital, involving 391 patients with acute pancreatitis who were categorized into non-MAKE30 (320 cases) and MAKE30 (71 cases) groups.

State-of-the-Art Review of Microcapsule Self-Repairing Concrete: Principles, Applications, Test Methods, Prospects.

Cement-based materials are widely used in construction worldwide, but they are vulnerable to environmental stressors and thermal fluctuations, leading to the formation of internal cracks that compromise structural integrity and durability. Traditional repair methods such as surface coatings, grouting, and groove filling are often costly and labor-intensive. In response, self-repairing technologies for cement-based materials have emerged as an innovative and promising solution, offering the potential to significantly extend the lifespan of structures and reduce maintenance costs.

Photocatalytic Consecutive Photoinduced Electron Transfer-Enabled C(sp)-H Pyridylation of Dihydroquinoxalin-2-ones.

A photocatalytic decyanative C(sp)-H pyridination of dihydroquinoxalin-2-ones with 4-cyanopyridines was developed by utilizing 4CzIPN as the photocatalyst. Mechanism studies show that this organophotocatalytic direct C(sp)-H pyridination undergoes a radical-radical cross-coupling pathway promoted by consecutive photoinduced electron transfer.

An initial exploratory clinical study and outcome assessment of gastrointestinal surgeries using advanced robotic-assisted techniques.

Background: In addition to the Da Vinci surgical robot, domestic surgical robots are being developed rapidly. Chinese Toumai® laparoscopic surgical robot was approved for urological surgery in 2022.This study aims to systematically evaluate the safety and efficacy of the Toumai® robotic surgical system in performing complex gastrointestinal surgeries.

Enhancing Thermal Management of Graphene Devices by Self-Assembled Monolayers.

Two-dimensional graphene has emerged as a promising competitor to silicon in the post-Moore era due to its superior electrical, optical, and thermal properties. However, graphene undergoes a strong degradation in its in-plane thermal conductivity when it is coupled to an amorphous substrate. Meanwhile, the weak van der Waals interaction between graphene and the dielectric substrate leads to high interfacial thermal resistance.

AASeg: Artery-aware Global-to-Local Framework for Aneurysm Segmentation in Head and Neck CTA Images.

Aneurysm segmentation in computed tomography angiography (CTA) images is essential for medical intervention aimed at preventing subarachnoid hemorrhages. However, most existing studies tend to overlook the topological characteristics of arteries related to aneurysms, often resulting in suboptimal performance in aneurysm segmentation. To address this challenge, we propose an arteryaware global-to-local framework for aneurysm segmentation (AASeg) using CTA images of head and neck.

Temperature sensitivity of methanogenesis and anaerobic methane oxidation in thermokarst lakes modulated by surrounding vegetation on the Qinghai-Tibet Plateau.

Understanding the balance between methane (CH) production (methanogenesis) and its oxidation is important for predicting carbon emissions from thermokarst lakes under global warming. However, the response of thermokarst lake methanogenesis and the anaerobic oxidation of methane (AOM) to warming, especially from Qinghai-Tibetan Plateau (QTP), is still not quantified. In this study, sediments were collected from 11 thermokarst lakes on the QTP.

Using hyperspectral imaging to predict the occurrence of delayed graft function.

Delayed Graft Function (DGF) is a prevalent complication in kidney transplantation (KT) that significantly affects allograft function and patient prognosis. Early and precise identification of DGF is crucial for improving post-transplant outcomes. In this study, we present KGnet, a predictive model leveraging hyperspectral imaging (HSI) to assess delayed graft function status.

Axial Impact Response of Carbon Fiber-Reinforced Polymer Structures in High-Speed Trains Based on Filament Winding Process.

The continuous increase in the operating speed of rail vehicles demands higher requirements for passive safety protection and lightweight design. This paper focuses on an energy-absorbing component (circular tubes) at the end of a train. Thin-walled carbon fiber-reinforced polymer (CFRP) tubes were prepared using the filament winding process.

Exploring Multiconnectivity and Subdivision Functions of Brain Network via Heterogeneous Graph Network for Cognitive Disorder Identification.

Brain serves as a critical cornerstone of human intelligence, which involves a series of complex neuropsychological activities that lead to the coordination of various functions in the brain network. In recent years, brain network analysis methods based on graph neural networks (GNNs) have attracted increasing attention for the identification of brain disorders. However, these methods generally assume that the brain network is a homogeneous graph while ignoring its heterogeneity among human brain activities, which is reflected in both the complex connectivity of the brain network and distinctive brain functions.

Different responses of soil bacterial community to plant-plant interactions under organic-inorganic fertilizers affect seedling establishment during subalpine forest succession.

Introduction: Rhizosphere bacterial community as a valuable indicator of soil quality and function, has been widespread studied. However, little knowledge is about the response of bacterial communities to plant-plant interaction and different fertilizers during secondary forest succession.

Methods: We conducted a field pot experiment applying organic and inorganic fertilizers to monocultures and mixed cultures of dominant plant species from mid- to late-successional stages (, , and ), and investigated the responses of plant growth and rhizosphere bacterial communities.

An active damping control strategy for suppressing LCL resonant point migration for three-phase grid-tied inverter.

LCL filters are extensively utilized in Grid-connected inverters due to their exceptional capability in suppressing high-frequency harmonics. The active damping method is commonly employed to mitigate the resonance peak of the LCL filter. However, this control strategy induces a shift in the natural resonance point.

Hyper-Interferon Sensitive Influenza Induces Adaptive Immune Responses and Overcomes Resistance to Anti-PD-1 in Murine Non-Small Cell Lung Cancer.

Despite recent advances in immunotherapy with immune checkpoint inhibitors, many patients with non-small cell lung cancer (NSCLC) fail to respond or develop resistance after an initial response. In situ vaccination (ISV) with engineered viruses has emerged as a promising antigen-agnostic strategy that can both condition the tumor microenvironment and augment antitumor T-cell responses to overcome immune resistance. We engineered a live attenuated viral vaccine, hyper-IFN-sensitive (HIS) virus, by conducting a genome-wide functional screening and introducing eight IFN-sensitive mutations in the influenza genome to enhance host IFN response.

Detection of Short-Chain Chlorinated Aliphatic Hydrocarbons through an Engineered Biosensor with Tailored Ligand Specificity.

Short-chain chlorinated aliphatic hydrocarbons (SCAHs), commonly used as industrial reagents and solvents, pose a significant threat to ecosystems and human health as they infiltrate aquatic environments due to extensive usage and accidental spills. Whole-cell biosensors have emerged as cost-effective, rapid, and real-time analytical tools for environmental monitoring and remediation. While the broad ligand specificity of transcriptional factors (TFs) often prohibits the application of such biosensors.

Repetitive Transcranial Magnetic Stimulation Alleviates MPTP-Induced Parkinson's Disease Symptoms by Regulating CaMKII-CREB-BMAL1 Pathway in Mice Model.

Background: Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive neuromodulation technique that shows promise for the treatment of Parkinson's disease (PD). However, there is still limited understanding of the optimal stimulation frequencies and whether rTMS can alleviate PD symptoms by regulating the CaMKII-CREB-BMAL1 pathway.

Methods: A PD mouse model was induced intraperitoneally with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and treated with 1 Hz, 5 Hz, and 10 Hz rTMS.

Design, Synthesis, and Antimicrobial Activity of Amide Derivatives Containing Cyclopropane.

As an important small organic molecule, cyclopropane is widely used in drug design. In this paper, fifty-three amide derivatives containing cyclopropane were designed and synthesized by introducing amide groups and aryl groups into cyclopropane through the active splicing method, and their antibacterial and antifungal activities were evaluated in vitro. Among them, thirty-five compounds were new compounds, and eighteen compounds were known compounds (, , , -, , and -).

An analysis of the safety of Sevoflurane drugs: A disproportionality analysis based on Food and Drug Administration Adverse Event Reporting System.

Sevoflurane is a volatile anesthetic that can tolerate inhalation induction and is widely used for inducing anesthesia due to its pleasant odor. As a drug that has been on the market for nearly 30 years, the vast majority of adverse reactions have been documented. This study aims to improve the adverse reactions related to Sevoflurane through the mining, organizing and analysis of Food and Drug Administration Adverse Event Reporting System database data.