Effects of preimplantation genetic testing for aneuploidy on embryo transfer outcomes in women of advanced reproductive age with no more than three retrieved oocytes.

Objective: To evaluate whether preimplantation genetic testing for aneuploidy (PGT-A) benefits women of advanced reproductive age (≥38 years old) with a diminished ovarian reserve (DOR; not more than three retrieved oocytes).

Design: A retrospective analysis comparing two groups: (a) PGT-A group: women who chose PGT-A and subsequent single re-warmed embryo transfers (ETs) and (b) non-PGT-A group: women who chose not to genetically test their embryos and underwent subsequent fresh or re-warmed ETs of one to two embryos on days 3 or 5.

Subjects: Two hundred and thirty patients underwent PGT-A therapy, with 49 of these individuals undergoing more than one PGT-A cycle.

Efficacy and safety of thalidomide in patients with β-thalassemia intermedia and major.

To investigate the short-term and long-term efficacy and safety of thalidomide in the treatment of intermediate and severe β-thalassemia. We analyzed patients with intermediate and severe β-thalassemia treated at our hospital from February 2019 to February 2024. Patients who received treatment for more than 3 months were included.

(Re)Conceptualizing Sex and Gender in Physical Education through Social Role Theory.

The line between gender and sex has become increasingly muddled in recent scientific literature, including within physical education. Tensions surrounding this topic are ever-increasing and definitions of the two are rarely consistent. For improving conceptual clarity for research, we adopted the Social Role Theory to offer spaces for researchers to explore how these two terms differ and relate by laying out a cyclical framework of biological, sociological, and psychological components.

Diagnosis of Autism Spectrum Disorder by Dynamic Local Graph-Theory Indicators Based on Electroencephalogram.

Background: Autism Spectrum Disorder (ASD) is a complex neurodevelopment disease characterized by impaired social and cognitive abilities. Despite its prevalence, reliable biomarkers for identifying individuals with ASD are lacking. Recent studies have suggested that alterations in the functional connectivity of the brain in ASD patients could serve as potential indicators.

Retraction Notice to: circFMN2 Sponges miR-1238 to Promote the Expression of LIM-Homeobox Gene 2 in Prostate Cancer Cells.

[This retracts the article DOI: 10.1016/j.omtn.

Association of Traditional dietary pattern with early and precocious puberty: a population-based cross-sectional study.

Background: Precocious puberty is an endocrine disease that is diagnosed by sex, age, and Tanner stage of puberty. This study aimed to investigate the association between various dietary patterns and early or precocious puberty, especially Traditional dietary patterns, which have been rarely investigated.

Methods: A total of 4085 primary school students in grades 1-3 (6-9 years) completed individual characteristic surveys, health examinations, and food frequency questionnaires (FFQs).

Paraspeckle protein NONO attenuates vascular calcification by inhibiting bone morphogenetic protein 2 transcription.

Vascular calcification is a pathological process commonly associated with atherosclerosis, chronic kidney disease, and diabetes. Paraspeckle protein NONO is a multifunctional RNA/DNA binding protein involved in many nuclear biological processes but its role in vascular calcification remains unclear. Here, we observed that NONO expression was decreased in calcified arteries of mice and patients with CKD.

Dynamic monitoring of aboveground biomass in inner Mongolia grasslands over the past 23 Years using GEE and analysis of its driving forces.

Aboveground biomass (AGB) in grasslands directly reflects the net primary productivity, making it a sensitive indicator of grassland resource quality and ecological degradation. Accurately estimating AGB over large regions to reveal long-term AGB evolution trends remains a formidable challenge. In this study, we divided Inner Mongolia Autonomous Region (IMAR) grasslands into three study regions based on their spatial distribution of grassland types.

Optimization of Flavonoid Extraction from Eucommia ulmoides pollen using Respond Surface Methodology and its biological activities.

Flavonoids, known for their abundance in Eucommia ulmoides pollen, possess diverse biological functions, including antioxidants, antibacterial agents, and anti-tumor properties. This study aims to establish effective parameters for flavonoid extraction from Eucommia ulmoides pollen using a microwave-assisted method, characterize the flavonoid composition of the extracted material, and explore its biological activities. Building upon the initial results from single-factor experiments, response surface methodology was employed to optimize the extraction parameters.

Reconstruction of Water-Filled Pipe Ultrasonic Guided Wave Signals in the Distance Domain by Orthogonal Matching Pursuit Based on Dispersion and Multi-Mode.

Ultrasonic guided waves (UGWs) in water-filled pipes are subject to more severe dispersion and attenuation than vacant pipes, posing significant challenges for defect identification and localization. To this end, a novel sparse signal decomposition method called orthogonal matching pursuit based on dispersion and multi-mode (DMOMP) was proposed, which utilizes the second-order asymptotic solution of dispersion curves and the conversion characteristics of asymmetric UGWs in the defect contact stage to reconstruct the dispersive signals and converts the time-domain dispersive signals to distance-domain non-dispersive signals by dispersion compensated time-distance mapping. The synthesized simulation results indicate that DMOMP not only exhibits higher reconstruction accuracy compared to OMP, but also reveals more accurate and stable mode recognition and localization compared to DOMP, which only considers the dispersion under perturbation and noise.

Controllable Regiodivergent Alkynylation of 1,3-Bis(Boronic) Esters Activated by Distinct Organometallic Reagents.

1,3-Bis(boronic) esters can be readily synthesized from alkylBpin precursors. Selective transformations of these compounds hold the potential for late-stage functionalization of the remaining C-B bond, leading to a diverse array of molecules. Currently, there are no strategies available to address the reactivity and, more importantly, the controllable regiodivergent functionalization of 1,3-bis(boronic) esters.

A Place-Based Conceptual Model (PBCM) of Neotricula aperta/Schistosoma mekongi habitat before and after dam construction in the Lower Mekong River.

In 1971, scientists from Mahidol University in Thailand and the Smithsonian Institution in the USA formed a research team to study a new species of Schistosoma in the Mekong River in Thailand and Laos. The studies, completed during 1971-1973, prior to the construction of any dams or restrictions to the natural flow regime of the Mekong River, provide a unique description of the natural ecological state of the river that can serve as a baseline for current research. The natural transmission of Schistosoma japonicum, Mekong Strain, was first reported on Khong Island, Laos in 1973 using sentinel mice.

A meta-analysis of the value of MRI-based VBQ scores for evaluating osteoporosis.

Objective: Osteoporosis is the most common skeletal disease in humans. Early onset of osteoporosis is usually asymptomatic, so early diagnosis is critical. The purpose of this study was to analyze the value of MRI-based VBQ scores for evaluating osteoporosis.

Performance of fish sludge solubilization and phototrophic bioconversion by purple phototrophic bacteria for nutrient recovery in aquaponic system.

Nutrient recovery from fish sludge in aquaponics is crucial to improve the economic output of a system sustainably and hygienically. Currently, fish sludge is treated using conventional anaerobic and aerobic mineralization, which does not allow the recovery of valuable nutrients in fish wastes. In this study, a two-stage approach (named as solubilization process and phototrophic bioconversion) is proposed to convert fish sludge into mineral nutrients and biomass nutrients using purple phototrophic bacteria (PPB), thereby promoting the growth of plants and fish simultaneously in aquaponics.

Quorum Sensing Is Required for the Colony Establishment of a Plant Phyllosphere Bacterium Rhodopseudomonas palustris Strain GJ-22.

The phyllosphere presents a hostile environment for many biocontrol agents; however, it is as significant as is the rhizosphere for plant health. Deploying biocontrol bacteria into the phyllosphere can efficiently suppress diseases; however, the lack of knowledge on the phyllosphere adaptive traits of biocontrol bacteria poses challenges. In this study, we demonstrated that Rhodopseudomonas palustris GJ-22 colonizes the phyllosphere by forming cell aggregates.

Gastrointestinal transit time of radiopaque ingested foreign bodies in children: experience of two paediatric tertiary centres.

Introduction: Foreign body (FB) ingestion is a common paediatric emergency. While guidelines exist for urgent intervention, less is known of the natural progress of FBs passing through the gastrointestinal tract (GIT). We reviewed these FB transit times in an outpatient cohort.

Role of nuclear receptors and in regulating molting and reproduction in (stål).

The nuclear receptors and are highly conserved and function to regulate molting and reproduction in both hemimetabolous and holometabolous insects. However, their roles in are largely unknown. In the present study, we discover that and are activated in the nymph stages by ecdysone signaling.

Bound states in the continuum based on the total internal reflection of Bloch waves.

A photonic-crystal slab can support bound states in the continuum (BICs) that have infinite lifetimes but are embedded into the continuous spectrum of optical modes in free space. The formation of BICs requires a total internal reflection (TIR) condition at both interfaces between the slab and the free space. Here, we show that the TIR of Bloch waves can be directly obtained based on the generalized Fresnel equations proposed.

Cognitive Load and Energy Balance Knowledge in High-School Physical Education.

Purpose: Guided by the cognitive load theory, the purpose of this study was to determine the impacts of cognitive load and school socioeconomic status-related environmental factors on ninth-graders' energy-balanced living knowledge gain.

Methods: A stratified random sample of high-school students ( = 150) participated in this study. Data were collected on students' knowledge gain, cognitive load, free and reduced-price meal rates, and student-to-teacher ratio.

Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL.

Recently, chimeric antigen receptor (CAR)-T cell therapy has shown great promise in treating haematological malignancies. However, CAR-T cell therapy currently has several limitations. Here we successfully developed a two-in-one approach to generate non-viral, gene-specific targeted CAR-T cells through CRISPR-Cas9.

A Simple Optical Aerosol Sensing Method of Sauter Mean Diameter for Particulate Matter Monitoring.

Mass concentration is a commonly used but insufficient metric to evaluate the particulate matter (PM) exposure hazard. Recent studies have declared that small particles have more serious impacts on human health than big particles given the same mass concentration. However, state-of-the-art PM sensors cannot provide explicit information of the particle size for further analysis.

Abiotic transformation of atrazine in aqueous phase by biogenic bixbyite-type MnO produced by a soil-derived Mn(II)-oxidizing bacterium of Providencia sp.

Recently, biogenic Mn oxides (BioMnO) are considered as the promising degradation agents for environmental organic contaminants. However, little information is available for the degradation of atrazine by BioMnO. In this work, BioMnO, generated by a soil-derived Mn(II)-oxidizing bacterium, Providencia sp.

Learning to Teach Again: What Professional Development Approach Matters?

Purpose: Informed by the constructivist learning theory, the purpose of this study was to determine the impact of three continuing professional development (CPD) approaches on student learning in a healthful living physical education curriculum.

Methods: Physical education teachers ( = 19) received one of the following CPD trainings: (a) , (b) , or (c) . The effect of each CPD method was determined by tracking student learning ( = 3,418) with a two-level linear mixed model.

The Missing Link? Middle School Students' Procedural Knowledge on Fitness.

Purpose: Guided by the declarative-procedural knowledge framework, the study attempts to identify middle school students' declarative (knowing what) and procedural (knowing how) fitness knowledge and the relationship between the two.

Methods: A sample of students ( = 291, age 11-14 years) from 24 middle schools took a grade-relevant standardized knowledge test on declarative fitness knowledge and received a semistructured interview designed to clarify their declarative and procedural knowledge.

Results: Most students were lacking in procedural knowledge to conduct fitness-enhancing physical activities.

Dynamic of land use, landscape, and their impact on ecological quality in the northern sand-prevention belt of China.

Changes in land use and landscapes have a direct impact on the regional eco-environment. It is of great importance to understand the change pattern of land use, landscapes, and their mechanism on the ecological quality, especially ecologically fragile areas. The northern sand-prevention belt (NSPB) is an important ecologically fragile area in China, which has a large influence on the ecological security of the entire country.