[Features of connective tissue dysplasia and prognosis of chronic gastroduodenal diseases in children of school age].

Compatibility of such signs, as not differentiated connective tissue dysplasia and chronic gastroduodenitis is considered. 170 patients of school age with the confirmed diagnosis chronic gastroduodenitis are surveyed with the purpose of revealing signs of connective tissue dysplasia. It is shown, that symptoms of connective tissue dysplasia meet more often at children with chronic gastroduodenitis, than at children without inflammatory gastroduodenal disease.

[New methods of assessing intoxication and blood cell response in patients with infectious toxicoses].

The microviscosity indexes of cell membranes of erythrocytes, neutrophils, and lymphocytes were estimated in children with acute respiratory diseases with and without infectious toxicosis. The erythrocyte microviscosity most completely reflects the degree of toxicosis. The ratio of membrane microviscosity indexes of neutrophils to that of lymphocytes demonstrates the specific response of blood cells to infectious toxic exposure.

[Phasic changes in the brain blood-flow indices of young children in the acute period of complicated pneumonia].

Cerebral hemodynamics has been studied rheoencephalographically in 39 infants early in the course of complicated pneumonia and in 19 healthy controls. The former exhibited phasic changes in cerebral circulation. On the disease day 3 and 10, a significant reduction in the blood flow took place.

[Rheologic properties of the blood in infants with complicated pneumonia].

Blood rheology was assessed in 23 infants with acute pneumonia complicated with respiratory infectious toxicosis during hospitalization to intensive care wards, a control group consisted of 19 healthy infants. Plasma viscosity, red cell deformability, surface architectonics, and aggregation were studied. Patients developed increased plasma viscosity, marked reduction of red cell deformability, and increased aggregation index parallelled by reduced rate of aggregate formation.

[Assessment of surface structure of blood cells by phase-contrast and scanning electron microscopy in children].

Study of red cell surface structure is a highly informative method for the assessment of the body status in health and disease. The authors have examined the surface red cell structure of infants in health and disease by phase-contrast and scanning electron microscopy and came to the conclusion on the high reliability of the data obtained by phase-contrast microscopy. They recommend this unsophisticated and informative method for clinical practice.

[Diagnosis of disorders of rheological properties of blood and central and cerebral hemodynamics in infants with complicated pneumonia].

A study was made of the rheological blood properties, microcirculation, central and cerebral hemodynamics in children of the first year of life with complicated pneumonia. On admission to the department of intensive care and resuscitation the patients demonstrated pronounced hemorheological and hemodynamic disorders which might in many respects determine the disease gravity. Based on an analysis of the clinical observations and hemodynamic findings 3 periods of complicated pneumonia were distinguished in such children: the critical period, stabilization and repair.

[Biological standardization of the gonadotropin-inhibiting factor].

The authors suggest a method of quantitative determination of the goandotropin-inhibiting factor in the urine; the principle of calculation of the activity of the standard preparation of the gonadotropin-inhibiting factor is presented. Investigation of the activity of the inhibitor in the individual portions of the urine of 6-8-year-old children demonstrated that the method of obtaining, testing and calculating the activity of the gonadotropin-inhibiting factor reflected quite adequately the biological activity of the extracts of child urine preventing the action of crude gonadotropins.