Publications by authors named "Chemezov S"

This paper reviews the methodological and technical possibilities of the application of modern imaging methods (ultrasonography, computer tomography and its variety spiral computer tomography, magnetic resonance tomography, endoscopic investigation) for the study of intravital anatomy of body regions, inner organs, their structures and cavities. It is shown that these methods provide the objective information on the position, dimensions, and structure of the objects under study Using the morphometric methods with further variation-statistical analysis gives the objective quantitative characteristics, allows to distinguish marginal and most common variants of form and dimensions of anatomical structures.

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Now there is no generally accepted practice of antibacterial therapy of acute sinusitis in outpatient clinics of Russia. Choice of antibacterial drugs is often made without consideration of the most probable causative agents of the infection. Out-of-date antibiotics used in many cases do not satisfy modern requirements.

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The programme was aimed at audit of the parameters of antibacterial therapy for acute otitis media in adult outpatients in 8 cities of Russia (Smolensk, Volgograd, Ekaterinburg, Yaroslavl, Nizhny Novgorod, Tyumen, Ryazan, Vladivostok). The information sources were the case records. The data from the records were structurally fixed in specially designed individual registration charts for further computer processing.

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The method of computer tomography was used to study the individual and age-related differences were found in the topography of pancreas, kidneys, abdominal aorta and in the shape of adrenal glands. Morphometric studies performed resulted in the description of the range of these differences and in the establishment of average quantitative parameters. It is concluded that the results of computer tomographic analysis may be used for the studies of intravital topography of the abdominal and retroperitoneal organs of individual patients and for description of variants of localization of different anatomical structures.

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The forms of vessels and muscular bundles localization in the eye rectal muscles were investigated by methods of morphometry and quantitative analysis. The vessels and the muscular bands may be disposed loose or compact as it has been shown. Inferior and medical rectal muscles the compact variant of bands distribution prevail and they are rich in vessels.

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Using morphometry with the following variational-statistical analysis the study of the structural reorganization of brain capillary bed in different model disturbances of intracranial venous circulation was performed. It was shown that in acute stage of venous congestion, obtained by different ways, capillary bed displayed reaction of one type, in chronic stage it was dependent on the level of the venous block. Integrative index of degrees of capillary bed blood supply is a value of its volume in 1 cubic millimeter brain parenchyma.

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Using histological morphometric and variation statistical methods it was demonstrated that in acute and chronic systemic venous congestion in cranial cavity changes in the number of opened capillaries, their cross sectional area and total length of capillary bed occur in brain structures. The above-mentioned changes cause alterations in blood supply of brain regions which objectively reflects reorganization of cerebral vascular bed in new conditions.

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Microcirculatory bed of the brain was studied in patients with cardiac and cardiopulmonary insufficiency. The findings on the biomicroscopic and histological changes in the vessels of the conjunctiva in experimental animals in the systemic venous stagnation were presented.

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In 43 test animals the state of the blood bed in the retrobulbar formations and the eyeball vasular tunic has been studied under venous congestion produced by ligation of the anterior vena cava (in dogs) and both external jugular veins (in rabbits). A complex of histological, histotopographic, morphometric and variation-statistical techniques has been used. The results obtained demonstrate that disturbances in the venous outflow in the anterior vena cava system produce certain responses in all parts of the retrotubular adipose tissue, of the eyeball muscles, of the optic nerve tunics, of the vascular tunic.

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