Publications by authors named "Chelsea Sutherland"

Article Synopsis
  • The study investigated the safety and effectiveness of omicron BA.1 monovalent and bivalent booster vaccines compared to the original mRNA-1273 vaccine in a large, randomized trial involving participants aged 16 and older.
  • Conducted in the UK, the trial assessed antibody responses and safety profiles, focusing on the immune response at day 29 after administration of the boosters.
  • A total of 3,098 participants were enrolled, with results showing differing immune responses between the new omicron boosters and the original vaccine, aiming for both non-inferiority and potential superiority.
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Political and economic transitions have had substantial impacts on forest conservation. Where transitions are underway or anticipated, historical precedent and methods for systematically assessing future trends should be used to anticipate likely threats to forest conservation and design appropriate and prescient policy measures to counteract them. Myanmar is transitioning from an authoritarian, centralized state with a highly regulated economy to a more decentralized and economically liberal democracy and is working to end a long-running civil war.

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Background: The global lapatinib expanded access programme provided access to lapatinib combined with capecitabine for women with HER2-positive metastatic breast cancer (MBC) who previously received anthracycline, taxane and trastuzumab.

Methods: Progression-free survival (PFS) and safety data for 356 patients recruited from the United Kingdom are reported. Efficacy was assessed in 162 patients from the five lead centres, including objective tumour response rate (ORR), time to disease progression (TTP) and efficacy in those with central nervous system (CNS) metastases.

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