Publications by authors named "Chelsea Michaud"
Background: In patients with humoral immunodeficiency, the progression of bronchiectasis has been known to occur despite adequate gammaglobulin therapy and in the absence of recurrent infections. This observation suggests that factors other than gammaglobulin replacement might play a part in the prevention of lung damage in this population. α-Antitrypsin deficiency can be associated with bronchiectasis, a chronic inflammatory lung disease.
View Article and Find Full Text PDFArticle Synopsis
- Penicillin desensitization is crucial for pregnant patients with severe penicillin allergies who also have syphilis.
- A pregnant patient with secondary syphilis experienced anaphylaxis during the desensitization process but was successfully treated with intramuscular epinephrine.
- Continuous fetal monitoring during the episode indicated that the fetus experienced stable conditions, suggesting that epinephrine has little to no immediate negative effects on the fetus in such situations.
Idiopathic pancreatitis in a patient with a STAT3 mutation.
Allergy Rhinol (Providence)
January 2016
Article Synopsis
- Hyperimmunoglobulin E syndrome (HIES) is a rare immune disorder causing severe skin and respiratory infections and involves high levels of immunoglobulin E.
- A patient with a known STAT3 deficiency related to HIES had extraimmune symptoms like unique facial features, skeletal fractures, and episodes of pancreatitis.
- Research indicates that STAT3 plays a crucial role in pancreatic health, and while mouse studies show STAT3 mutations worsen pancreatitis, the link in humans has not been fully established until this case was reported.