Publications by authors named "Chelsea Krueger"

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Background: There are few studies describing aminoglycoside pharmacokinetics during continuous renal replacement therapy (CRRT).

Objective: To characterize the effect of CRRT on aminoglycoside clearance and volume of distribution ().

Methods: Retrospective observational pharmacokinetic study of adult critically ill oncologic patients who received a first dose of amikacin or tobramycin during CRRT between February 2012 and May 2017.

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Article Synopsis
  • Patients on dual antiplatelet therapy (DAPT) who needed urgent procedures were assessed for safety and effectiveness of cangrelor bridging, given its quick onset and offset.
  • The study included 41 mostly older Caucasian males; 22% experienced bleeding events, mostly minor, with a single severe case.
  • Eschewing oral P2Y12 inhibitors in favor of cangrelor may be a viable option for patients needing temporary interruption of antiplatelet therapy.
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