Publications by authors named "Chelsea Frost"

Spinal injury and back pain are a common problem facing patients seeking medical care including athletes, which can lead to significant disability, medical costs, and impaired performance for these patients. Rehabilitation including core muscle stabilization, Kinesio taping, and flexibility have been shown to help with treatment and prevention. Critical factors such as equipment, technique, and rule changes can also be an important part of spine injury prevention.

View Article and Find Full Text PDF

Study Design: Observational study.

Objectives: To determine the publication rate of podium presentations from the North American Spine Society (NASS) annual meetings from the years 2009 to 2011.

Methods: In April 2015, a PubMed search was conducted using titles from the paper presentations as well as the authors.

View Article and Find Full Text PDF

Study Design: Observational Study.

Objective: To evaluate the publication rate of podium presentations from the Scoliosis Research Society (SRS) and the International Meeting of Advanced Spinal Techniques (IMAST) annuals meeting and to compare the publication rate of SRS/IMAST meetings to other orthopedic and spine meetings.

Summary Of Background Data: Although various publication rates from orthopedic meetings have been reported, recent publication rates from the SRS and IMAST annual meetings are not known.

View Article and Find Full Text PDF

To our knowledge, there are no reports in the literature of patients with Parkinson disease (PD) developing upper cervical spine infections. Our objective is to present a case of upper cervical epidural abscess in a patient with PD and to review upper cervical spine infection. We present the patient's presentation, physical examination, imaging findings, and management as well a review of the literature.

View Article and Find Full Text PDF

Various websites are dedicated to rating physicians. The goals of this study were to: (1) evaluate the prevalence of orthopedic surgeon ratings on physician rating websites in the United States and (2) evaluate factors that may affect ratings, such as sex, practice sector (academic or private), years of practice, and geographic location. A total of 557 orthopedic surgeons selected from the 30 most populated US cities were enrolled.

View Article and Find Full Text PDF

Study Design: Observational study.

Objective: To evaluate the publication rate of podium presentations from the Cervical Spine Research Society (CSRS) annual meeting and to evaluate the publication rate of award-winning papers from the CSRS annual meeting.

Summary Of Background Data: Although various publication rates from Orthopaedic meetings have been reported, the publication rates from the CSRS annual meetings are not known.

View Article and Find Full Text PDF

Background: c-Fos is a cellular proto-oncogene which dimerizes with c-Jun proto-oncogene to form AP-1 transcription factor, which upregulates transcription of genes involved in proliferation and cancer formation. Four cardiac hormones, that is, long-acting natriuretic peptide (LANP), vessel dilator, kaliuretic peptide (KP) and atrial natriuretic peptide (ANP) with anticancer effects in vivo are potent inhibitors of the Ras-MEK 1/2-ERK 1/2 kinase cascade and signal transducer and activator of transcription-3 (STAT-3) that activate c-Fos and c-Jun. These four cardiac hormones were investigated for their effects on proto-oncogenes c-Fos and c-Jun within the nucleus of cancer cells.

View Article and Find Full Text PDF

Signal transducers and activators of transcription (STATs) are the final "switches" that activate gene expression patterns that lead to human malignancy. Extracellular signal-regulated kinases (ERK 1/2) activate STAT 3; four cardiovascular hormones inhibit ERK 1/2 kinases, leading to the hypothesis that they may also inhibit STATs. These four cardiac hormones, i.

View Article and Find Full Text PDF

Background: Vascular endothelial growth factor (VEGF) helps control tumour growth via causing new capillaries growth in tumours. Four cardiac hormones [i.e.

View Article and Find Full Text PDF

Background: Four cardiac peptide hormones, namely vessel dilator, long-acting natriuretic peptide (LANP), kaliuretic peptide, and atrial natriuretic peptide (ANP) have anticancer effects.

Materials And Methods: The effects of these four cardiac hormones on human c-Jun-N-terminal kinase 2 (JNK2) were examined in human small cell lung cancer and human prostate cancer cells.

Results: Vessel dilator, LANP, kaliuretic peptide and ANP maximally reduced expression of JNK2 by 89%, 56%, 45%, and 28%, respectively (each at p<0.

View Article and Find Full Text PDF