Publications by authors named "Chelsea Carle"

Article Synopsis
  • Previous studies linked cancer diagnoses with increased COVID-19 death risk, but many didn’t differentiate between long-term survivors and those recently diagnosed or treated, nor did they consider age factors.
  • The research aimed to provide clearer evidence regarding the risk of COVID-19-related death in individuals with active or recent cancers during the pre-vaccination period, analyzing 39 studies that adjusted for age and gender.
  • Results indicated that people with recent cancer diagnoses have a significantly higher risk of dying from COVID-19, especially for those with lung or hematological cancers, with the risk decreasing over time since treatment.
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Background: Early reports suggested that COVID-19 patients with cancer were at higher risk of COVID-19-related death. We conducted a systematic review with risk of bias assessment and synthesis of the early evidence on the risk of COVID-19-related death for COVID-19 patients with and without cancer.

Methods And Findings: We searched Medline/Embase/BioRxiv/MedRxiv/SSRN databases to 1 July 2020.

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Background: The early COVID-19 literature suggested that people with cancer may be more likely to be infected with SARS-CoV-2 or develop COVID-19 than people without cancer, due to increased health services contact and/or immunocompromise. While some studies were criticised due to small patient numbers and methodological limitations, they created or reinforced concerns of clinicians and people with cancer. These risks are also important in COVID-19 vaccine prioritisation decisions.

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Background: Globally, tobacco smoking remains the largest preventable cause of premature death. The COVID-19 pandemic has forced nations to take unprecedented measures, including 'lockdowns' that might impact tobacco smoking behaviour. We performed a systematic review and meta-analyses to assess smoking behaviour changes during the early pre-vaccination phases of the COVID-19 pandemic in 2020.

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Objective: There is growing interest in more risk-based approaches to breast cancer screening in Australia. This would require more detailed reporting of BreastScreen data for factors of interest in the assessment and monitoring of risk-based screening. This review assesses the current and potential availability and reporting of BreastScreen data for this purpose.

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Background: There is uncertainty on how multiparametric MRI (mpMRI) and MRI-targeted biopsy (MRI-TB) can be best used to manage low-risk prostate cancer patients on Active Surveillance (AS). We performed a scoping review to evaluate the benefits and harm associated with four different biopsy scenarios in which mpMRI can be implemented in AS.

Methods: Medline, Embase and Cochrane Library databases (1 January 2013-18 September 2020) were searched.

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Objective: To assess the use of diet and the use of exercise for prostate cancer (and/or its treatments' side effects) by long-term survivors and whether such use is associated with selected socio-demographic, clinical, health-related quality-of-life (HRQOL) and psychological factors.

Design, Setting And Participants: Population-based cohort study in New South Wales, Australia of prostate cancer survivors aged <70 years at diagnosis and who returned a 10-year follow-up questionnaire.

Methods: Validated instruments assessed patient's HRQOL and psychological well-being.

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