Publications by authors named "Chelsae R Watters"
Mol Ther Oncolytics
June 2023
Article Synopsis
- Vesiculoviruses are promising candidates for cancer treatment due to their rapid replication and ability to target tumors effectively while avoiding immune system detection.
- Researchers developed a synthetic chimeric virus called VMG, which combines elements from Morreton virus and vesicular stomatitis virus, and found it effectively induced cell death in various sarcoma types across different species.
- Initial safety tests in healthy mice showed no toxicity, and while VMG didn't suppress tumors in one model, it successfully stimulated immune responses, showing potential as a new oncolytic virotherapy for sarcoma.
