Publications by authors named "Chek Tung Ngo"

Article Synopsis
  • The study investigates how Peperomia pellucida reduces inflammation in ARPE-19 eye cells exposed to high glucose and advanced glycation end products (AGEs) by exploring specific signaling pathways (NF-κB and PPAR-γ).
  • Both the methanolic extract and ethyl acetate fraction of P. pellucida showed no toxicity to the cells and provided protection against cellular stress caused by high glucose levels and AGEs.
  • Key phytochemicals in P. pellucida demonstrated strong binding to inflammatory proteins, suggesting their potential role in inhibiting the inflammatory response in these retinal cells.
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The extraction of plant bioactive compounds from Platycladus orientalis (L.) Franco remains a great challenge due to the different chemical groups. This study aimed to compare the bioactive compounds with enzyme inhibitory effect from P.

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Peperomia pellucida (L.) Kunth is a medicinal plant used to manage inflammatory illnesses such as conjunctivitis, and gastrointestinal and respiratory tract disorders in tropical and subtropical regions. However, little is known about its pharmacological mechanism of action against eye diseases.

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