Adherence to the dietary approaches to stop hypertension (DASH) and risk of pancreatic steatosis.

Background: The Dietary Approach to Stop Hypertension (DASH) has shown positive effects on various health factors that may be related to pancreatic steatosis (PS). This study aimed to investigate the association between adherence to the DASH diet and the risk of developing PS.

Methods: This case-control study was conducted on 278 patients diagnosed with gallstone disease and referred to Taleghani Hospital (Tehran, Iran).

Mechanistic insights into cisplatin response in breast tumors: Molecular determinants and drug/nanotechnology-based therapeutic opportunities.

Breast cancer continues to be a major global health challenge, driving the need for effective therapeutic strategies. Cisplatin, a powerful chemotherapeutic agent, is widely used in breast cancer treatment. However, its effectiveness is often limited by systemic toxicity and the development of drug resistance.

Therapeutic Potential of PLK1, KIF4A, CDCA5, UBE2C, CDT1, SKA3, AURKB, and PTTG1 Genes in Triple-Negative Breast Cancer: Correlating Their Expression with Sensitivity to GSK 461364 and IKK 16 Drugs.

The treatment of triple-negative breast cancer (TNBC) has been associated with challenges due to the lack of expression of ER, PR, and HER2 receptors in tumor cells. This study aimed to identify genes with potential therapeutic targets in TNBC. Data from the cancer genome atlas regarding breast cancer (BC) were downloaded.

Crosslinked Polydiallyldimethylammonium Chloride Adsorbent for the Selective Separation of Rhenium Ions from Pregnant Leach Solutions.

The depletion of valuable mineral reserves has rendered effluents generated from mining and industrial processing activities a promising resource for the production of precious elements. The synthesis and improvement of new adsorbents to extract valuable compounds from industrial wastes and pregnant leach solutions, besides increasing wealth, can play a significant role in reducing environmental concerns. In this work, a new and low-cost adsorbent for the selective extraction of rhenium (perrhenate ions, ReO) was synthesized by the free-radical polymerization (FRP) of a diallyl dimethylammonium chloride monomer (quaternary amine) in the presence of a crosslinker.

Whole exome sequencing identifies novel pathogenic variants in TGM1 and ALOX12B in patients with hereditary ichthyosis.

Background: Hereditary ichthyosis is a clinically and genetically heterogeneous disorder associated with more than 50 genes with TGM1, ALOX12B, and ALOXE3 being the most prevalent. Establishing an accurate diagnosis is important for effective genetic counseling and optimal patient management.

Objective: We studied the diagnostic value of whole exome sequencing (WES) in a small case series with hereditary ichthyosis.

miRNAs and exosomal miRNAs in lung cancer: New emerging players in tumor progression and therapy response.

Non-coding RNAs have shown key roles in cancer and among them, short RNA molecules are known as microRNAs (miRNAs). These molecules have length less than 25 nucleotides and suppress translation and expression. The functional miRNAs are produced in cytoplasm.

Nano-curcumin supplementation in patients with mild and moderate acute pancreatitis: A randomized, placebo-controlled trial.

We aimed to investigate whether nano-curcumin as an anti-inflammatory agent is effective in patients with mild and moderate AP. This study was a double-blind, parallel-arm randomized controlled trial conducted at Taleghani hospital, Tehran, Iran. Eligible subjects with a diagnosis of mild and moderate AP were randomly assigned to receive either two doses of nano-curcumin (40 mg) or placebo (control) daily for 2 weeks.

Micronutrient intake and risk of ulcerative colitis: A meta-analysis of observational studies.

Background & Aims: Ulcerative colitis (UC) poses a challenge to patients' health status and lifestyle. Micronutrient intake has been associated with the risk of UC, but the association has been inconsistent. Therefore, we performed a meta-analysis to clarify the overall association between micronutrient intake, as potentially modifiable risk factors, and the risk of UC.

Relationship between diet quality and depression among Iranian older adults in Tehran.

Background: Depression is one of the prevalent mental disorders that is common in older ages. Evidence suggests that dietary intake status may potentially be associated with depression. However, this association has not been well studied in older adults, and the nature of the association remains unclear.

Physical and mental growth and development in children with congenital hypothyroidism: a case-control study.

Introduction: The clinical complications of congenital hypothyroidism such as brain disorders are very subtle and are not recognizable in infancy period. They are recognizable when it is too late for treatment or prevention. General screening of newborns is effective in diagnosing congenital hypothyroidism and initiating initial treatment.

Impact of career choice motivation on academic burnout in senior dental students: A cross-sectional study.

Background: Motivation triggers all human activities including learning and lack of career motivation can lead to decreased efficiency. This study assessed the association between academic burnout and career choice motivation in senior dental students.

Methods: This cross-sectional study was performed on senior dental students of all four dental schools in Tehran in 2017.

Trends in the drowning mortality rate in Iran.

Objective: The WHO estimates the global incidence of death by drowning to be about 300 000 cases per year. The objective of this study was to estimate the trend in mortality due to drowning in all provinces of Iran in all age groups and both genders from 1990 to 2015.

Study Design: The National and Subnational Burden of Diseases (NASBOD) project is a comprehensive project in Iran.

The Correlation of Microstructure and Mechanical Properties of In-Situ Al-MgSi Cast Composite Processed by Equal Channel Angular Pressing.

In this paper, the effect of equal channel angular pressing (ECAP) on microstructure and mechanical properties of hypereutectic Al-20%MgSi and Al-15%MgSi, as well as hypoeutectic Al-10%MgSi composites has been investigated. After fabricating the composites by in-situ casting, the composites were processed using the ECAP process up to two passes at room temperature. Microstructural studies have been carried out using a field emission scanning electron microscopy equipped with an energy dispersive X-ray spectrometer.

Liver cirrhosis mortality at national and provincial levels in Iran between 1990 and 2015: A meta regression analysis.

Background: Liver cirrhosis mortality number has increased over the last decades. We aimed to estimate the liver cirrhosis mortality rate and its trends for the first time by sex, age, geographical distribution, and cause in Iran.

Method: Iranian Death Registration System, along with demographic (Complete and Summary Birth History, Maternal Age Cohort and Period methods) and statistical methods (Spatio-temporal and Gaussian process regression models) were used to address the incompleteness and misclassification and uncertainty of death registration system to estimate annual cirrhosis mortality rate.

Annual Trends of Gastrointestinal Cancers Mortality in Iran During 1990-2015; NASBOD Study.

Background: Gastrointestinal (GI) neoplasms are among the most common cancers in Iran. This study aimed to measure annual trends in mortality rates from GI cancers in Iran between 1990 and 2015.

Methods: This study was part of an ongoing study termed the 'National and Subnational Burden of Diseases' study in Iran.

A New Method for Surgical Abdominal Mass Closure After Abdominal Fascial Dehiscence Using Nasogastric Tube and Hemovac Perforator: A Case-Series Study.

Background: As the challenge for finding the best abdominal incision closure technique continues, surgeons are aiming to minimize postoperative wound complications such as wound dehiscence and hernia as an acute or late manifestation. In order to achieve this goal, several abdominal opening and closure techniques have been tried. In this article, we describe a method in which we used a nasogastric tube (NGT) in mass closure for patients with fascial dehiscence.

Measuring Iran's success in achieving Millennium Development Goal 4: a systematic analysis of under-5 mortality at national and subnational levels from 1990 to 2015.

Background: Child mortality as one of the key Millennium Development Goals (MDG 4-to reduce child mortality by two-thirds from 1990 to 2015), is included in the Sustainable Development Goals (SDG 3, target 2-to reduce child mortality to fewer than 25 deaths per 1000 livebirths for all countries by 2030), and is a key indicator of the health system in every country. In this study, we aimed to estimate the level and trend of child mortality from 1990 to 2015 in Iran, to assess the progress of the country and its provinces toward these goals.

Methods: We used three different data sources: three censuses, a Demographic and Health Survey (DHS), and 5-year data from the death registration system.

National and Subnational Patterns of Cause of Death in Iran 1990-2015: Applied Methods.

Background: Causes of death statistics provide crucial health intelligence in national and international communities. An efficient death registration system provides reliable information for health policy system. In many developing countries, death registration systems face a degree of misclassification and incompleteness.

Burden of Vaccine-Preventable Diseases-Measles, Tetanus, Diphtheria and Whooping Cough-in Iran: Findings from the GBD study 2010.

Background: Vaccination has been one of the most successful and cost-effective public health interventions in the last century and has saved millions of lives. In 1984, the Expanded Program on Immunization (EPI) was launched in Iran as one of the main components of Primary Health Care (PHC). 

Objectives: We aimed to investigate the burden of four vaccine-preventable diseases from 1990 to 2010 in Iran.

[Radiologic implantation of central venous portal systems in the forearm].

Purpose: To assess the safety and effectiveness of fluoroscopic guided brachial implanted central-venous miniport systems.

Patients And Methods: In 32 oncological patients a central-venous miniport system (Vital-Port, CPC-Cook) was implanted in the forearm. The group included 15 women and 17 men (range 33-78, mean 56 years).