Publications by authors named "Chee Woei Yap"
Adjunctive rosuvastatin for rifampicin-susceptible pulmonary tuberculosis (rs-PTB) shows no effect on microbiological or radiological outcomes in a phase IIb randomised, controlled trial (NCT04504851). We explore the impact of adjunctive rosuvastatin on 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) imaging in a sub-study of 24 participants. Changes in standardised uptake value (SUVmax, SUVmean), Total Metabolic Volume, (TMV), Total Lesion Glycolysis (TLG), cavity diameter and volume, between week 0 and week 8 post-randomisation, are evaluated.
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- Contrast-enhanced medical imaging improves tissue differentiation and helps study organ function but can lead to complications in patients with renal failure.
- Iodinated contrast media in CT scans can cause acute kidney injury, and gadolinium-based agents in MRI can result in nephrogenic systemic fibrosis, necessitating careful patient assessment.
- Alternatives like ultrasound contrast agents may be safer for patients with kidney issues, emphasizing the importance of collaboration between clinical teams and radiologists to decide the best imaging approach.
Pulmonary arteriovenous malformations (PAVMs) are uncommon, predominantly congenital direct fistulous connections between the pulmonary arteries and pulmonary veins, resulting in a right to left shunt. Patients with PAVMs are usually asymptomatic with lesions detected incidentally when radiological imaging is performed for other indications. In this review, we discuss the classification and radiological features of PAVMs as well as their treatment and follow-up options, with a particular focus on percutaneous endovascular techniques and the evolution of the available equipment for treatment.
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