[Percutaneous laser diskectomy in cervical osteochondrosis].

The paper presents early and late outcomes of treatment in 62 patients undergone paracentetic laser "diskectomy" for discogenic compressed syndromes of the neck. It shows the efficiency of surgery for radicular (92.9%) and myelopathic (92.

[Conservative treatment of breast cancer].

The paper is concerned with clinical characterization of 81 breast cancer patients after conservative radio- and hormonotherapy. Of the total number of patients 47 suffered from inoperable tumors as a result of local spreading, 30 patients had serious contraindications for the operation, and 4 patients refused surgical intervention. Of the total number of patients 85% were aged over 50, 69%--over 60.

[An experience with the conservative treatment of breast cancer in middle-aged and elderly women].

Advantages of conservative treatment of inoperable breast cancer in old and elderly age are discussed on the basis of an analysis of data on 30 cases. A split-course radical radiotherapy was combined with a prolonged tamoxifen treatment. Complete regression of tumor was registered in 16 out of 23 followed-up patients, while more than 50% regression--in I case.

[Experience in the organization of ambulatory chemotherapy at the All-Union Oncologic Research Center of the USSR Academy of Medical Sciences].

The recent advances have made it possible for chemotherapy to be used for cancer control under the conditions of out-patient clinics. Within 5 years, 9,000 out-patients had received at the Center 10-day courses of chemotherapy which was free from toxic complications and produced a therapeutic effect similar to that observed in in-patients. The out-patient chemotherapy service saved 177,140 in-patient/days which is an equivalent of running a 500 bed specialized cancer hospital during 12 months.

[Functional relationships between the midbrain tegmentum and the supraoptico-hypophyseal neurosecretory system of the white rat hypothalamus].

Bilateral electrolytic destruction of the paramedian midbrain caudal tegmentum caused the appearance in the internal part of the hypothalamic supraoptic nucleus of neurosecretory cells with low functional activity and degenerating forms (dark-stained and pycnomorphic cells); in the posterior hypophysis the destructed gigantic terminal varicosities (Herring bodies) were revealed; the posterior hypophysis contained a subnormal amount of neurosecret; the vasopressin-antidiuretic hormone level in blood plasma was reduced. Painful stimulation of animals with the destructed midbrain tegmentum revealed the functional insufficiency of the supraoptic hypophyseal neurosecretory system (SHNS). The results obtained permit considering that the paramedian midbrain tegmentum exerts a modulating influence upon the SHNS function during stress.

[Palliative radiation therapy of malignant tumor metastases to the bones].

The results obtained in irradiation of 106 patients with metastases of different malignant tumors in the skeleton are reported. Radiotherapy was carried out on a distance gamma-apparatus by two fractions, with a single dose of 650 or 850 rad. As a result of the therapy, pains disappeared in 32 patients, and in 60 patients these were diminished considerably.

[Chemoradiation therapy of inoperable lung cancer].

The results of utilization of different variants of the complex therapy in 416 patients with inoperable lung cancer are reported. 5-fluoruracil, cyclophosphan, methotrexate, chrysomallin were employed as antitumor drugs. Radiotherapy was carried out on a distance gamma machine.