Clinical utility of PCR compared to conventional culture and sensitivity testing for management of complicated urinary tract infections in adults: Part II.Evaluation of diagnostic concordance, discordant results, and antimicrobial selection efficacy.

Purpose: Complicated urinary tract infections (cUTIs) are difficult to manage due to their polymicrobial nature and resistance to standard therapies. In current clinical practice, the management of a cUTI often starts with broad-spectrum antimicrobials until culture and sensitivity (C&S) results are available, but these diagnostic delays further hinder treatment efficacy. Polymerase Chain Reaction (PCR) offers a faster alternative.

Clinical utility of PCR compared to conventional culture and sensitivity testing for the management of complicated urinary tract infections in adults: Part I. Assessment of clinical outcomes, investigator satisfaction scores, and turnaround times.

Purpose: Managing complicated urinary tract infections (cUTIs) poses significant challenges, often resulting in the overprescription of empiric antibiotics. This approach exposes patients to multiple antimicrobials and raises the risk of inadequate treatment efficacy. The purpose of this study is to assess and compare the clinical utility of molecular testing (PCR) versus conventional culture and sensitivity (C&S) in managing cUTI, to identify optimal management strategies for cUTI patients.

Potential effects of postmenopausal labial agglutination on the urinary system.

Labial agglutination (LA) can affect prepubertal or postmenopausal women. LA commonly affects prepubertal girls, but the rate at which LA affects postmenopausal women is unknown, with only a few documented case reports. Symptoms of LA include vulvovaginal pain, dysuria, dyspareunia, and urinary incontinence/urinary symptoms.

Retrospective Analysis of Sexual Function After Transvaginal Mesh Surgery.

Introduction: Despite ample research regarding the impact of reconstructive surgery on anatomic/functional outcomes of pelvic organ prolapse (POP), including incidence of dyspareunia, evidence regarding sexual outcomes is equivocal.

Aim: To assess changes in sexual function in women followed up for at least 12 months after transvaginal mesh surgery for POP.

Methods: We conducted a retrospective review of women who underwent surgery for POP using different mesh products between 2008 and 2019.

Urethral carcinoma: A compilation of case studies and research findings.

There are three major recognized histological types for primary urethral carcinoma (PUC). These include transitional cell carcinoma (55%), squamous cell carcinoma (21.5%), and adenocarcinoma (16.

Role of vaginal mesh hysteropexy for the management of advanced uterovaginal prolapse.

Objective: To determine the role of vaginal mesh hysteropexy in the management of advanced genital organ prolapse as assessed by subjective and objective parameters.

Study Design: Retrospective case series of 77 women followed for at least 1 year after vaginal mesh hysteropexy performed for stage III or greater uterovaginal prolapse. The primary outcome was Pelvic Organ Prolapse Quantification (POP- Q) stage < II and no subjective bothersome bulge and no further interventions for prolapse.