Publications by authors named "Che Jiang"
Background: Repetitive transcranial magnetic stimulation (rTMS) showed potentially beneficial effects for the treatment of post-traumatic stress disorder (PTSD). Low-frequency (LF) rTMS decreases neuronal excitability and may have better safety compared to high-frequency (HF) rTMS. However, there lacks meta-analysis specifically focusing on LF rTMS.
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- This study explored the impact of Functional Electrical Stimulation (FES) and Transcranial Direct Current Stimulation (tDCS) on limb recovery and quality of life after a stroke when used alongside Occupational Therapy (OT).
- The research involved analyzing 8 studies with a total of 358 participants, comparing outcomes between groups receiving only OT and those receiving OT with either FES or tDCS.
- Findings showed that both FES and tDCS improved post-stroke recovery, with FES demonstrating significantly better outcomes in enhancing motor function compared to tDCS.
Background: Diffuse lower-grade glioma (DLGG) in the central lobe is a challenge for safe resection procedures. To improve the extent of resection and reduce the risk of postoperative neurological deficits, we performed an awake craniotomy with cortical-subcortical direct electrical stimulation (DES) mapping for patients with DLGG located primarily within the central lobe. We investigated the outcomes of cortical-subcortical brain mapping using DES in an awake craniotomy for central lobe DLGG resection.
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- ICU nurses are at high risk for PTSD, and previous methods of reducing intrusive memories through visuospatial tasks have shown mixed results.
- In a randomized controlled trial, ICU nurses played a music tapping game after experiencing a stressful CPR event to measure its effect on the emotionality of their memories.
- The study found that playing the game with background music significantly reduced the emotional impact of traumatic memories compared to other conditions, suggesting that the experience of "flow" can enhance the effectiveness of memory reconsolidation interventions.
Article Synopsis
- The study aimed to investigate how interictal epileptiform discharge (IED) source connectivity relates to structural couplings in the cortex of patients with temporal lobe epilepsy (TLE).
- Researchers utilized 3D-MRI and EEG data from 59 TLE patients, analyzing cortical structures and IED sources through various statistical methods.
- Results indicated that structural couplings in the brain were negatively correlated with IED source connectivity, highlighting the significance of managing IEDs in TLE treatment.
The incidence of posttraumatic stress disorder (PTSD) following stroke ranges from 6.5 % to 25 %. Presently few studies have focused on its treatment.
View Article and Find Full Text PDFBackground: Stroke is a devastating disease and can be sufficiently traumatic to induce post-traumatic stress disorder (PTSD). Post-stroke PTSD is attracting increasing attention, but there was no study assessing the psychometric properties of the PCL-5 in stroke populations. Our study was conducted to examine the psychometric properties of the PTSD Checklist for DSM-5 (PCL-5) in Chinese stroke patients.
View Article and Find Full Text PDFPost-traumatic stress disorder (PTSD) can develop after stroke attacks, and its rate ranges from 4 to 37% in the stroke population. Suffering from PTSD not only decreases stroke patient's quality of life, but also relates to their non-adherence of treatment. Since strokes often recur and progress, long-term medical management is especially important.
View Article and Find Full Text PDFBrain structural connectivity sub typing in unilateral temporal lobe epilepsy.
Brain Imaging Behav
October 2022
To categorize and clinically characterize subtypes of brain structural connectivity patterns in unilateral temporal lobe epilepsy (TLE). Voxel based morphometry (VBM) and surfaced based morphometry (SBM) analysis were used to detect brain structural alterations associated with TLE from MRI data. Principal component analysis (PCA) was performed to identify subtypes of brain structural connectivity patterns.
View Article and Find Full Text PDFLongitudinal changes of motor cortex function during motor recovery after stroke.
Top Stroke Rehabil
May 2023
Article Synopsis
- The study used fMRI and behavioral assessments to examine how the motor cortex reorganizes after a stroke, aiming to improve rehabilitation methods.
- Researchers recruited 20 stroke patients and healthy volunteers, conducting fMRI scans and tests on motor skills over a three-month period.
- Results indicated that stroke patients showed increased motor activation in the brain's areas responsible for movement, particularly in the hemisphere opposite the affected hand, suggesting adaptive changes in brain function post-stroke.
According to the reconsolidation theory, memories can be modified through the destabilization-reconsolidation process. The rodent perirhinal cortex (PER; Brodmann areas 35 and 36) critically participates in the process of fear conditioning. Previous studies showed that some of the parahippocampal regions are critical for contextual fear memory reconsolidation.
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- Metabolic reprogramming in somatic cell reprogramming involves increased glycolysis and decreased mitochondrial activity, but the exact mechanisms remain unclear.
- Various scientific studies have proposed different roles for autophagy and mitochondrial dynamics in this process, making it challenging to compare results.
- Our research indicates that mitochondrial remodeling in reprogramming does not involve mitophagy and emphasizes that suppression of the mTORC1-PGC1 pathway is crucial, contributing to a better understanding of metabolic changes related to development, aging, and cancer.
The aim of this study was to investigate the occurrence, correlated factors and prognosis of posttraumatic stress symptoms (PTSS) in patients with Cushing's disease (CD). A total of 49 patients who were newly diagnosed with CD and underwent transsphenoidal surgery in our hospital from April 2015 to August 2017 were asked to participate in this study. Another group of 49 age and sex matched healthy control participants were also included for comparison.
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- The study aimed to assess the occurrence of PTSD in patients diagnosed with low-grade gliomas (LGGs) three months after surgery and its relationship with survival rates over five years.
- Out of 219 patients studied, 16% were diagnosed with PTSD, with younger age and frontal lobe involvement being significant predictors.
- Patients with PTSD displayed higher levels of anxiety and depression and experienced a lower quality of life, with the presence of PTSD linked to an increased risk of mortality over the five-year follow-up period.
Risk of probable posttraumatic stress disorder in patients with trigeminal neuralgia.
Psychol Health Med
April 2019
The object of this study was to reveal the occurrence, risk factors and prognosis of posttraumatic stress disorder (PTSD) in patients with trigeminal neuralgia (TN). Adult patients who were diagnosed with TN were prospectively collected from our neuroscience center. Among the 103 patients recruited, thirty (29.
View Article and Find Full Text PDFPosttraumatic stress disorder after a first-ever intracerebral hemorrhage in the Chinese population: A pilot study.
Appl Neuropsychol Adult
September 2020
Article Synopsis
- This study focused on the prevalence of PTSD in patients after intracerebral hemorrhage (ICH), identifying risk factors and long-term effects.
- It involved 64 patients and utilized DSM-5 for PTSD diagnosis, with assessments at 3 and 12 months showing significant differences in mental health between those with and without PTSD.
- The findings revealed higher PTSD rates in females, increased rates of minimally invasive surgery, and a notable portion of patients eventually recovering from PTSD symptoms within a year post-ICH.
Article Synopsis
- Long noncoding RNAs, specifically ANRIL located on Chromosome 9p21.3, play a key role in regulating gene expression and are associated with several diseases, including tumors and coronary artery disease.
- ANRIL has been identified as a candidate gene that may contribute to the formation of intracranial aneurysms (IAs), though its molecular mechanisms are not well understood.
- The paper proposes four potential mechanisms by which ANRIL may influence IA development, including cell cycling and involvement with specific proteins, suggesting ANRIL could serve as a future molecular marker or therapeutic target for IAs.
New Insights in Minimally Invasive Surgery for Intracerebral Hemorrhage.
Front Neurol Neurosci
September 2016
The poor clinical outcome of acute intracerebral hemorrhage (ICH) relates closely to the bleeding amount per unit of time and the hematoma position in the brain. Removal of an intracerebral hematoma in time can effectively improve clinical prognosis. Minimally invasive surgery (MIS) for the treatment of ICH is the main clinical method that is currently used, despite the lack of large-scale, clinical, multi-center, randomized controlled trials.
View Article and Find Full Text PDFPurpose: To evaluate the perioperative safety and mid-term prognosis (≤12 months) of HydroSoft coils in treating ruptured aneurysms at the anterior circulation compared with bare platinum coils.
Materials And Methods: Patients with aneurysmal subarachnoid hemorrhages admitted to our hospital between January 2009 and March 2012 were retrospectively analyzed. According to strict inclusion and exclusion criteria, cases were selected and classified into two groups: In group A, HydroSoft coils were used as the primary filling coils (≥40 % of total coil length); in group B, only bare platinum coils were used.
Purpose: To determine the safety and efficacy of endovascular therapy for the treatment of basilar artery dissection (BAD).
Methods: Patients with BAD admitted to our hospital from June 2002 to December 2011 were retrospectively reviewed. Strict inclusion and exclusion criteria were made.
Article Synopsis
- The study investigates how hemodynamic factors (blood flow dynamics) and morphological characteristics contribute to the risk of rupture in cerebral aneurysms, specifically using mirror posterior communicating artery aneurysms as a model.
- Researchers compared 8 patients with ruptured and unruptured aneurysms, focusing on five morphological and three hemodynamic parameters using advanced imaging technology.
- Findings revealed that ruptured aneurysms had significantly lower wall shear stress (WSS), higher low WSS area percentage, and higher aspect ratio (AR), indicating that both hemodynamics and morphology are crucial in assessing the rupture risk of aneurysms.