Publications by authors named "Chayan Manna"
Article Synopsis
- The StAR protein plays a crucial role in the initial steps of neuro/steroid production, which is important for hormone balance especially as we age.
- Aging leads to changes in the immune system and decreases in neurosteroids, increasing the risk of Alzheimer's disease (AD), particularly in women.
- Research shows that alterations in StAR levels and neurosteroid production are linked to AD pathology, highlighting the potential for retinoid signaling as a therapeutic target for improving brain health and reducing dementia risk.
Background: Vortioxetine and venlafaxine are antidepressants which have shown established efficacy to treat major depressive disorder (MDD). There are no studies that compared them for their efficacy in cognitive symptoms of depression. The study aimed to compare the effect of vortioxetine and venlafaxine on the change in cognitive scores in adults with MDD.
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