Clinical improvements in temporospatial gait variables after a spinal tap test in individuals with idiopathic normal pressure hydrocephalus.

Idiopathic Normal Pressure Hydrocephalus (iNPH) is a neurological condition that often presents gait disturbance in the early stages of the disease and affects other motor activities. This study investigated changes in temporospatial gait variables after cerebrospinal fluid (CSF) removal using a spinal tap test in individuals with idiopathic normal pressure hydrocephalus (iNPH), and explored if the tap test responders and non-responders could be clinically identified from temporospatial gait variables. Sixty-two individuals with iNPH were recruited from an outpatient clinic, eleven were excluded, leaving a total of 51 who were included in the analysis.

Relationships between amyloid levels, glucose metabolism, morphologic changes in the brain and clinical status of patients with Alzheimer's disease.

Objective: The current study was conducted to improve the understanding of relationships between regional cortical amyloid load, glucose metabolism, cortical morphology (volume), and severity of clinical symptoms in patients with AD, MCI, and age-matched controls.

Methods: To objectivize the radiological evaluation of patients with suspected AD, head-to-head multi-modality imaging studies were conducted using MRI and PET/CT with [F]FDG and [F]AV45 for visualization and quantitation of brain morphology, glucose metabolism, and amyloid levels, respectively. A total of 84 subjects was studied, including 33 patients with AD, 31 patients with MCI, and 20 age-matched healthy controls (HC).

Feasibility Study of Language Lateralization using Thai Version of Language Paradigm for Functional MRI in Clinical Service.

Objective: To evaluate the concordance of language lateralization between functional magnetic resonance imaging (fMRI) using Thai version of language paradigm and Wada test or awake surgery with direct cortical brain stimulation (DCS).

Material And Method: Retrospective study of thirteen patients (3 males and 10 females with mean age of 33.9 years old) with epilepsy (7 cases) or brain tumor (6 cases) was performed.

Comparison of High Resolution T2W and Gd-T1W of MRI Internal Acoustic Canal in Sensorineural Hearing Loss.

Objective: To evaluate the concordance of high resolution T2-weighted (HR-T2W) and Gd-T1W for mass detection in internal acoustic canal (IAC) or cochlear in sensorineural hearing loss (SNHL).

Material And Method: The retrospective study of patients with SNHL undergoing magnetic resonance imaging (MRI) IAC protocol was performed. HR-T2W and Gd-T1W were separately reviewed for any mass in IAC or cochlear.

Comparison of High Resolution T2W and Gd-T1W of MRI Internal Acoustic Canal in Sensorineural Hearing Loss.

Objective: To evaluate the concordance of high resolution T2-weighted (HR-T2W) and Gd-T1W for mass detection in internal acoustic canal (IAC) or cochlear in sensorineural hearing loss (SNHL).

Material And Method: The retrospective study of patients with SNHL undergoing magnetic resonance imaging (MRI) IAC protocol was performed. HR-T2W and Gd-T1W were separately reviewed for any mass in IAC or cochlear.

Computerized Tomographic Angiography for Detection of Cerebral Vasospasm after Ruptured Intracranial Aneurysm.

Objective: Digital subtraction angiography (DSA) is the gold standard to diagnose cerebral vasospasm but it is usually not available due to lack of expertise and proper equipment. The present study aimed to compare the diagnostic accuracy of brain computerized tomographic angiography (CTA) in detecting cerebral vasospasm after intracranial aneurysmal rupture.

Material And Method: Between January 2011 and October 2014, 20 patients who were suspected of cerebral vasospasm after aneurysmal subarachnoid hemorrhage (SAH) were prospectively enrolled.

Diagnostic performance of advanced MRI in differentiating high-grade from low-grade gliomas in a setting of routine service.

Objective: To evaluate the usefulness of advanced MRI techniques in differentiating high-grade (HGG) from low-grade gliomas (LGG).

Material And Method: Sixty-four patients with suspected gliomas were prospectively evaluated by conventional and advanced MRI studies including MR spectroscopy (MRS), diffusion tensor imagining (DTI), and dynamic susceptibility contrast (DSC) MRI. The parametric measurements of metabolic profile, cerebral blood volume, flow (CBV, CBF), apparent diffusion coefficient (ADC), fractional anisotropy, and their ratios by internal normalization were analyzed to differentiate LGG from HGG.

Diagnostic performance of perfusion MRI in differentiating low-grade and high-grade gliomas: advanced MRI in glioma, A Siriraj project.

Background: To determine the usefulness of the perfusion MRI technique at Siriraj Hospital for differentiating between high- and low-grade gliomas by using pathological results as the gold standard.

Material And Method: The authors prospectively investigated 64 consecutive patients who were suspected as cerebral glioma from prior conventional imaging. Cerebral perfusion study was achieved during the first pass of a bolus of gadolinium-based contrast agent.

Value of diffusion tensor imaging in differentiating high-grade from low-grade gliomas.

Objective: To determine the usefulness of diffusion tensor imaging (DTI) in differentiating high-grade glioma (HGG) from low-grade glioma (LGG).

Material And Method: Patients with cerebral gliomas underwent conventional MRI and DTI before surgery. All proven pathologies were classified into two groups, i.

Ischemic cerebrovascular disease and calcified intracranial vertebrobasilar artery: A case-control study by using cranial CT.

Objective: To evaluate the association of intracranial vertebrobasilar (VB) artery calcification and ischemic cerebrovascular disease of the posterior circulation.

Material And Method: A cross-sectional, retrospective, case-control study was performed in 198 patients with cranial CT Presence of the posterior fossa infarction was disclosed in 104 patients of the case group. Absence of the posterior fossa infarction in 94 patients were defined as a control group.

MRI study of intracranial hydrodynamics and ventriculoperitoneal shunt responsiveness in patient with normal pressure hydrocephalus.

Objective: To determine the predictor for shunt responsive cases in patient with normal pressure hydrocephalus (NPH) by means of magnetic resonance imaging (MRI) cerebrospinal fluid (CSF) flow study at Siriraj hospital.

Material And Method: The retrospective study was performed in patients suspected NPH and underwent MRI CSF flow measurement. 2D-phase contrast technique (Achieva, 3 Tesla Philips system) was used as CSF flow analysis.

Vertebral body compression fracture: discriminating benign from malignant causes by diffusion-weighted MR imaging and apparent diffusion coefficient value.

Objective: To evaluate the diagnostic performance of apparent diffusion coefficient (ADC) value in discriminating benign from malignant vertebral compression fracture.

Material And Method: 22 symptomatic patients with compression fracture of vertebra referred for conventional MRI spines during January 2009-March 2010 underwent additional diffusion weighted MR techniques. Evaluation of diffusion weighted MR imaging and quantified ADC value from reconstructed ADC map were performed.

Clinical application of susceptibility weighted imaging: exploring from routine service.

To evaluate the usefulness of susceptibility weighted imaging (SWI) in clinical brain MRI. Retrospective study was performed after approval from institution Ethical Committee. The brain MRIs with SWI were selected from data base of the radiology department.

Evidence of vascular compromise over the visual cortex during migrainous headache: a case report with MRI study.

The objective of the present study was to demonstrate MRI evidence of vascular compromise as seen in a 17-year-old female presenting with migrainous headache. The patient had been experiencing migrainous headache 2 days ago. She had visual auras lasting for a few hours before the attack.

Reliability study of white matter rating scale for the dementia and disability in Thai Elderly Project.

Objective: To study the reliability of white matter rating scale on magnetic resonance imaging (MRI) of elderly patients in the urban community of Bangkok.

Material And Method: One hundred elderly with clinical diagnosis of cognitive impairment in the urban community around Siriraj Hospital underwent cranial MRI according to the Dementia and Disability in Thai Elderly Project. The axial T1wi, T2wi, and fluid attenuated inversion recovery (FLAIR) were separately assessed by two neuroradiologists.

Diagnostic accuracy of perfusion CT in differentiating brain abscess from necrotic tumor.

Objective: To evaluate the diagnostic accuracy of perfusion computed tomography (CTP) in differentiating between brain abscess and necrotic tumor.

Material And Method: Prospective study was performed in patients suspected of a space taking lesion in the brain. CTP was done at the suspected levels and post-processing measurement of cerebral blood volume (CBV), cerebral blood flow (CBF), mean transit time (MTT), and permeability surface index (PS) were evaluated at ring enhanced area, central non-enhanced area, edema and contralateral normal brain.

Radiographic chest findings and clinical correlations in leptospirosis.

Objective: To determine the clinical presentations, radiographic chest findings, and their correlation in patients with leptospirosis.

Design: A cross sectional study.

Setting: Between July 2001- December 2002 at 3 hospitals in North Eastern Thailand.

Scrub typhus: chest radiographic and clinical findings in 130 Thai patients.

Objective: To describe chest radiographic findings and their clinical correlation in patients with scrub typhus diagnosed in Thailand and to determine abnormalities that assist in the diagnosis of scrub typhus.

Material And Method: Between July 2001 and December 2002, 130 patients with scrub typhus admitted to three hospitals in the northeastern Thailand were studied. Data of clinical presentations and chest radiographic findings, reviewed by two radiologists who were unaware of the final diagnosis, were analyzed.

MRI of multiple sclerosis in Thai patients.

Objective: Evaluate the MRI findings of multiple sclerosis (MS) in Thai patients and compare these with the McDonald criteria for dissemination in space.

Material And Method: A retrospective study was performed by reviewing clinical and MRI records of patients attending MS clinic at Siriraj Hospital. Only patients with complete clinical and MRI data were included in the present study.

Magnetic resonance imaging of Asians with multiple sclerosis was similar to that of the West.

Magnetic resonance imaging (MRI) of the brain is the most important paraclinical diagnostic test in multiple sclerosis (MS). The appearance of MRI in Asians with MS is not well defined. We retrospectively surveyed the first brain and spinal cord MRI in patients diagnosed to have MS, according to Poser's criteria in seven regions throughout Asia to define the MRI changes among Asians with MS.

HRCT of pulmonary tuberculosis mimics malignancy: a preliminary report.

Objective: To evaluate potential predictors of high resolution CT (HRCT) findings of pulmonary mass caused by tuberculosis (Tbc).

Material And Method: A retrospective study of chest HRCT was performed in 10 patients diagnosed as pulmonary Tbc. The size, characteristics of lesions, enhancement and mediastinal lymphadenopathy were interpreted.

The limited protocol MRI in diagnosis of lumbar disc herniation.

Objective: To assess agreement in detection of lumbar disc herniation (LDH) between limited and full protocol MRI.

Material And Method: 123 patients who requested lumbar MRI for diagnosis of disc herniation were assessed The full protocol MRI composed of sagittal T1-wi, sagittal T2-wi and axial T2-wi was performed on each patient. The sagittal T2-wi was selected as the limited protocol MRI.