Isolation and molecular characterization of fowl adenovirus from inclusion body hepatitis cases in Western India during 2019-2021.

Background: Inclusion body hepatitis (IBH) resulted in a substantial economic loss in Western India during 2019 to 2021.

Aims: The study aimed to characterize fowl adenovirus (FAdV) from field outbreaks.

Methods: The study was conducted on 290 liver samples from 66 poultry flocks.

Seroprevalence and Risk Factors Associated with Leptospirosis in High-Risk Occupational Groups in the State of Gujarat as Determined by IgM ELISA and MAT Test: A Cross-Sectional Study.

Background: Leptospirosis is a reemerging zoonosis affecting humans and animals worldwide in tropical and subtropical countries. The study was conducted to estimate the seroprevalence of leptospirosis in high-risk occupational groups (cattle farm workers, poultry farm workers, and slaughterhouse workers) in the state of Gujarat and to determine related risk factors for leptospirosis.

Methods: Using an interview-guided questionnaire, a cross-sectional study was conducted involving 123 people in high-risk occupational groups (namely, cattle farm workers, poultry farm workers, and slaughterhouse workers) from five districts of the state of Gujarat, India.

Dynamics of Antibody Response to Covishield Vaccine after 6 Months: A Longitudinal Prospective Study.

Objectives: To study the dynamics of antibody responses in the real world up to 6 months following two Covishield vaccination doses and evaluate its correlation with age.

Materials And Methods: From March 2021 to February 2022, a prospective, longitudinal study of healthcare workers (HCWs) from a dedicated COVID-19 hospital was conducted. Institutional Ethics Committee permission was obtained.

Understanding the molecular mechanism of arsenic and ammonia toxicity and high-temperature stress in Pangasianodon hypophthalmus.

The current investigation explores the mechanisms of ammonia and arsenic toxicity, along with high-temperature stress, which other researchers rarely addressed. Pangasianodon hypophthalmus was exposed to low doses of ammonia and arsenic (1/10th of LC, 2.0 and 2.

Multifunctional role of dietary copper to regulate stress-responsive gene for mitigation of multiple stresses in Pangasianodon hypophthalmus.

It is an urgent needs to address climate change and pollution in aquatic systems using suitable mitigation measures to avoid the aquatic animals' extinction. The vulnerability and extinction of the aquatic animals in the current scenario must be addressed to enhance safe fish food production. Taking into consideration of such issues in fisheries and aquaculture, an experiment was designed to mitigate high temperature (T) and low pH stress, as well as arsenic (As) pollution in fish using copper (Cu) containing diets.

SARS-CoV-2 Antibody Response Following COVID-19 Vaccination, a Longitudinal Study.

Background: The objective was studying the antibody response following immunization with COVID-19 vaccines.

Material And Methods: It was a longitudinal study of healthcare workers (HCWs). Two groups were taken, Group 1 had taken first dose of the COVID-19 vaccine, at least 3 weeks have passed.

Isolation and molecular characterization of infectious bursal disease virus circulating in western and central India.

Background: Infectious bursal disease (IBD) caused substantial economic loss in central and western India during 2020 and 2021.

Aims: The study was conducted to characterize IBD virus (IBDV) from field outbreaks.

Methods: The study was conducted on 360 samples from 42 poultry flocks.

Molecular phylodynamics of fowl adenovirus serotype 11 and 8b from inclusion body hepatitis outbreaks.

Fowl adenovirus (FAdV) serotypes are involved in a variety of clinical manifestations in poultry and has resulted in substantial economic loss to the poultry farmers. Despite the endemicity of Inclusion body hepatitis (IBH) in South Asian countries, including India, its etiology is not well studied. In western India, the rural poultry flocks obtained from the vaccinated parents were experiencing disease outbreaks with substantial economic losses due to heavy outbreaks and mortality.

Performance of broiler chicken on dietary supplementation of protected organic acids blend.

1. The fatty acid coated organic acids blend was evaluated for its potential as a growth promoter.2.

To Study Adverse Effect following Immunization (AEFI) and COVID-19 Infection amongst COVID-19 Vaccine Benefeciaries.

Unlabelled: COVID-19 vaccines have been rolled out recently in several parts of the world. Little is known about the post-vaccination experience outside of clinical trial conditions. The aim of this study was to investigate the adverse effects and infection rate of vaccinated people in a community scenario.

Molecular phylodynamics of infectious bursal disease viruses.

The present study was conducted to study the molecular phylodynamics of the Indian field IBDVs. A total of 13 organized commercial poultry farms and 29 village poultry flocks were recruited in the study. The broiler flocks showed 15.

An observational study to find association between Hypertension and severe and fatal COVID-19 infection in COVID dedicated hospital, Mumbai.

Introduction: World Health Organization (WHO) has declared COVID-19 outbreak as a "public health emergency of international concern" on January 31, 2020. After that the epidemic spread rapidly around the world. Chronic non-communicable diseases were identified as risk factors for SARS-CoV-2.

Epidemiological study to assess the impact of COVID-19 pandemic on the occurrence of monsoon-related diseases in the city of Mumbai.

Background: The onset of monsoons in Mumbai poses an additional health disease burden in the form of rising vector-borne and water-borne diseases such as dengue, malaria, leptospirosis, hepatitis, typhoid, chikungunya, and acute gastroenteritis. These monsoon-related illnesses are preventable with hygienic and sanitation measures that are likely to have been adopted during COVID-19 pandemic.

Aim: To assess the impact of COVID-19 pandemic on the occurrence of monsoon-related diseases in the city of Mumbai and find out determinants of variations if any.

Assessment of Risk Factors for COVID-19 in Health Care Workers: A Nested Case-Control Study.

Objectives: To study the risk factors for SARS-CoV-2 infection in health care workers (HCWs) exposed to COVID-19 patients.

Material And Methods: This was a nested case-control study of health care workers(HCWs) in a Dedicated COVID Hospital(DCH). The data collection was done from Dec 2020 to Feb 2021.

A comparative cross-sectional analysis on outcomes of Covid-19 patients requiring dialysis.

Context: Coronavirus Disease 2019 (COVID-19) was declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. COVID-19 disproportionately affects patients with pre-existing comorbidities including those undergoing dialysis at intermittent intervals. These patients requiring renal replacement therapy like intermittent hemodialysis have a preponderance to go into severe clinical states.

Ghost cell.

Ghost cells (GCs) have been a curious topic since a great deal of time. Extensive research has been done to deduce the true characteristics and formation of these cells. GCs are balloon-shaped, elliptical, pale eosinophilic epithelial cells with pyknotic nuclei, leaving only a faint outline.

An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery.

The development of vaccines is one of the most significant medical accomplishments which has helped to eradicate a large number of diseases. It has undergone an evolutionary process from live attenuated pathogen vaccine to killed whole organisms or inactivated toxins (toxoids), each of them having its own advantages and disadvantages. The crucial parameters in vaccination are the generation of memory response and protection against infection, while an important aspect is the effective delivery of antigen in an intelligent manner to evoke a robust immune response.

Clinical, hematobiochemical, and pathological findings and therapeutic management of viperine snake envenomation in zebu cattle.

The present investigation was carried out to study the epidemiology, clinical signs, bleeding profile, kidney function, and pathology and to evaluate the therapeutic protocol for viperine snake envenomation in zebu cattle over a period of 14 years. A total of 98 cases of viperine bite were reported with the highest incidence during monsoon months in grazing male zebu cattle. Ascending swelling over the affected limb with lameness or asymmetrical swelling over the face with dyspnea was a consistent clinical finding.

Swollen liquid crystalline mesophase assisted synthesis of GO-PANI nanocomposite as a fluorescent probe for purines.

This article focuses on the use of graphene oxide-polyaniline (GO-PANI) nanocomposite as fluorescent probe for sensing of adenine (A) and guanine (G). Swollen liquid crystalline mesophase were used for the synthesis of graphene oxide-polyaniline nanocomposite. GO-PANI nanocomposite showed enhanced fluorescent at 441 nm (ƛ  = 361 nm) on interaction of purines viz A and G solutions in dimethyl sulfoxide, GO exhibited quenching at 540 nm (ƛ  = 261 nm).

Development of Novel Octanoyl Chitosan Nanoparticles for Improved Rifampicin Pulmonary Delivery: Optimization by Factorial Design.

A novel hydrophobic chitosan derivative, octanoyl chitosan (OC) with improved organic solubility was synthesized, characterized, and employed for the preparation of rifampicin (Rif) encapsulated nanoparticle formulations for pulmonary delivery. OC was characterized to confirm acyl group substitution and cytotoxicity in A549 epithelial lung cells. OC nanoparticles were produced by the double emulsion solvent evaporation technique without cross-linking and characterized for particle size distribution, morphology, crystallinity, thermal stability, aerosol delivery, and drug release rate.

Structural evaluations and temperature dependent photoluminescence characterizations of Eu(3+)-activated SrZrO3 hollow spheres for luminescence thermometry applications.

This research is focused on the temperature sensing ability of perovskite SrZrO3:Eu(3+) hollow spheres synthesized via the sol-gel method followed by heating. The Rietveld refinement indicated that the precursors annealed at 1100 °C were crystallized to form orthorhombic SrZrO3. SrZrO3 particles exhibited non-agglomerated hollow spherical morphology with an average particle size of 300 nm.