Effect of antiplatelet and anticoagulant medications on implant survival: a long-term retrospective cohort study.

Purpose: This large-scale retrospective study aimed to examine the long-term effect of antiplatelet and anticoagulant medications intake on dental implant treatment outcome.

Materials And Methods: This study retrospectively examined data from patients who underwent dental implant procedures at several university dental clinics within the BigMouth network between 2011 and 2022. Patients' characteristics including age, gender, ethnicity, race, tobacco use, systemic medical conditions and intake of antiplatelets and anticoagulants were analyzed.

Large language models in periodontology: Assessing their performance in clinically relevant questions.

Statement Of Problem: Although the use of artificial intelligence (AI) seems promising and may assist dentists in clinical practice, the consequences of inaccurate or even harmful responses are paramount. Research is required to examine whether large language models (LLMs) can be used in accessing periodontal content reliably.

Purpose: The purpose of this study was to evaluate and compare the evidence-based potential of answers provided by 4 LLMs to common clinical questions in the field of periodontology.

No association between periodontitis extent, severity, and progression rate with dental implant failure.

Objective: To analyze the relationship between extent, severity, and rate of progression of periodontitis with the implant outcome.

Methods: Dental records of adult patients who had attended the dental clinics of the universities contributing data to the BigMouth network between 2011 and 2022 seeking implant therapy were evaluated. Patients' records were furthered examined for a periodontal diagnosis based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions.

Survival rate of implants performed at sites of previously failed implants and factors associated with failure: A retrospective investigation.

Background/purpose: Although reimplantation is currently a common treatment procedure, little information on reimplantation success or failure is available in the literature. The purpose of the present investigation was to evaluate the survival rate of dental implants that were performed in sites of previously failed implants and identify factors associated with the treatment outcome.

Materials And Methods: This retrospective study is based on a cohort of patients rehabilitated with dental implants in the dental clinics of the universities contributing data to the BigMouth network between 2011 and 2022.

Relationship of Medication Intake and Systemic Conditions with Periodontitis: A Retrospective Study.

Objectives: To examine the potential relationship of medication intake and systemic conditions with periodontitis.

Methods And Materials: A total of 1985 patient records with a diagnosis of periodontal health and stage III and IV periodontitis were included in the analysis. Demographic characteristics, the number of missing teeth, patient-reported medical conditions and medication intake as well as smoking habits were recorded.

Periodontal Disease, Tooth Loss, and Systemic Conditions: An Exploratory Study.

Background: Although systemic medical conditions are associated with periodontitis and tooth loss, large-scale studies that include less prevalent systemic conditions are needed. The purpose of the study was to investigate the link between periodontal disease and tooth loss with systemic medical conditions in a large and diverse population.

Methods: Dental charts of adult patients who had attended the dental clinics seeking dental therapy of the universities contributing data to the BigMouth network and accepted the protocol of the study were included.

Retrospective analysis of 50,333 implants on implant failure and associated patient-related factors.

Purpose: The aim of this investigation was to retrospectively evaluate the long-term implant loss rates and to identify associations between implant failure and patient-related factors in a sample of patients who had consecutively received implant therapy in ten dental universities in the United States using a large database.

Methods: Dental records of adult patients who had attended the dental clinics of the universities contributing data to the BigMouth network between 2011 and 2022 seeking dental therapy were evaluated. Information regarding patients' characteristics including age, gender, ethnicity, race, tobacco use and systemic medical conditions were extracted from patients' files.

Association between Periodontitis Extent, Severity, and Progression Rate with Systemic Diseases and Smoking: A Retrospective Study.

Background: The aim of this study was to analyze the relationship between extent, severity (stage), and rate of progression (grade) of periodontitis with systemic diseases as well as smoking using a large database.

Methods: Patients' records identified in the BigMouth Dental Data Repository with a periodontal diagnosis based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions were evaluated. Patients were further categorized based on extent, severity, and rate of progression.

Complexity of Recent Earthquake Swarms in Greece in Terms of Non-Extensive Statistical Physics.

Greece exhibits the highest seismic activity in Europe, manifested in intense seismicity with large magnitude events and frequent earthquake swarms. In the present work, we analyzed the spatiotemporal properties of recent earthquake swarms that occurred in the broader area of Greece using the Non-Extensive Statistical Physics (NESP) framework, which appears suitable for studying complex systems. The behavior of complex systems, where multifractality and strong correlations among the elements of the system exist, as in tectonic and volcanic environments, can adequately be described by Tsallis entropy (), introducing the -exponential function and the entropic parameter that expresses the degree of non-additivity of the system.

Prevalence and risk indicators of peri-implantitis: a university based cross-sectional study.

Objectives: To assess the prevalence of peri-implantitis and identify risk and protective indicators of peri-implantitis in a population that underwent implant therapy in a university dental clinic.

Method And Materials: Randomly selected patients from a postgraduate university dental clinic were invited to participate. Clinical and radiographic examinations were recorded.

Dental implant failure and bone augmentation: A retrospective study.

Background: To retrospectively assess the failure rate of implants placed in augmented and non-augmented sites and to investigate whether the time of implant and bone placement are associated with the risk of implant failure in a university setting.

Material And Methods: In this retrospective study, data were retrieved from the electronic patient database of the University of Minnesota School of Dentistry, USA to identify patients older than 18 years of age who received dental implant treatment. Patient characteristics and the adequacy of available bone were retrieved from the patients' dental records and analyzed.

Local drug delivery in the treatment of furcation defects in periodontitis: a systematic review.

Objectives: To evaluate the effect of subgingival administration of various antimicrobials and host-modulating agents in furcation defects as an adjunct to scaling and root planing (SRP) compared to SRP alone or combined with placebo.

Methods: A systematic review was carried out using MEDLINE-PubMed, Embase, and Scopus for articles up to October 2022 in addition to hand searches. All longitudinal studies that evaluated the effect of subgingival application of antimicrobial and host-modulating agents in furcation defects as adjuncts to SRP compared to SRP alone or SRP + placebo with at least 3 months of follow-up were eligible for inclusion.

The Predictive Role of the Triglyceride/Glucose Index in Patients with Hypercholesterolemia and Acute Ischemic Stroke.

Background: The triglyceride/glucose index (TyG) reflects insulin resistance and predicts the risk of acute ischemic stroke (aIS). However, it is uncertain if this index predicts the severity and outcome of aIS because studies that addressed this question are few and all were performed in Asian subjects. Moreover, there are no studies that focused on patients with hypercholesterolemia.

Dental implant failure and factors associated with treatment outcome: A retrospective study.

Purpose: The purpose of the present study was to retrospectively 1) investigate the association between implant-, patient- and bone-related parameters with the risk of implant failure; 2) analyze the survival rates of dental implants placed in a university clinical setting.

Methods: Data were retrieved from patient charts from the University of Minnesota School of Dentistry to identify patients older than 18 years of age who received dental implant treatment by faculty, residents or students in the university dental clinics. Implant-, patient- and bone-related parameters such as implant system, length, diameter, jaw, region, installation protocol, gender, smoking, medical history, history of periodontal disease, self-reported oral parafunctions, type of bone, and operator were manually retrieved and analyzed.

Clinical Effectiveness of Herbal Oral Care Products in Periodontitis Patients: A Systematic Review.

Background: The use of herbal products in oral cavity has shown an increased popularity and potential benefits due to their additional anti-inflammatory and antioxidant properties as well as the lack of side effects related to their use.

Objective: To assess the clinical effectiveness of herbal dental products (mouthwash, dentifrice, gel) when compared to conventional products or placebo in periodontitis patients.

Material And Methods: A systematic review with 22 studies was carried out using MEDLINE/Pubmed, EMBASE and Web of Science databases in addition to hand searches.

Survival Rates and Factors Affecting the Outcome Following Immediate and Delayed Implant Placement: A Retrospective Study.

Background: Immediate implant placement into extraction sockets has become a widely acceptable treatment option to decrease treatment time and enhance esthetics. The objectives of this study were to assess and compare the survival rates of immediate and delayed implant treatment as well as to investigate the effect of patient- and site-related variables on the treatment outcome in a large-scale population-based study. Methods: Dental records of patients who received implant therapy were retrieved from the electronic records of the University of Minnesota School of Dentistry.

Expression of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after non-surgical periodontal treatment: A systematic review.

Periodontitis is a preventable and treatable multifactorial chronic inflammatory disease that can lead to irreversible periodontal destruction and tooth loss. Wnt signaling and its regulators play an important role in periodontal inflammation, destruction, regeneration, and reconstruction. This systematic review aimed at investigating the involvement of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after periodontal treatment.

Periodontal disease progression and gene polymorphisms: results after 3 years of active periodontal treatment.

Background: Although non-surgical periodontal treatment is considered the gold standard, a subgroup of patients displays recurrence/progression of periodontitis after treatment. The aim of the present prospective study was to assess the effect of IL-6 -572 G/C and IL-10 -592 C/A gene polymorphisms on the risk of disease recurrence/progression at 3 years following non-surgical periodontal treatment.

Methods: Thirty-seven patients diagnosed with chronic periodontitis received oral hygiene instructions and non-surgical periodontal treatment and were monitored for 3 years.

Postextraction ridge preservation by using dense PTFE membranes: A systematic review and meta-analysis.

Statement Of Problem: The use of dense polytetrafluoroethylene (dPTFE) membranes in alveolar ridge preservation may help reduce the risk of bacterial contamination and infection, maintaining the soft-tissue anatomy. However, systematic reviews on their efficacy in postextraction sites are lacking.

Purpose: The purpose of this systematic review and meta-analysis was to assess the efficacy of alveolar ridge preservation with dPTFE membranes when used alone or in combination with bone grafting materials in postextraction sites.

Flapless application of enamel matrix derivative in non-surgical periodontal treatment: A systematic review.

Background And Objective: To assess the effects of the flapless application of enamel matrix derivative (EMD) in combination with non-surgical periodontal treatment (NSPT) when compared to non-surgical periodontal treatment alone in adult patients.

Material And Methods: An electronic literature search was conducted in MEDLINE, Scopus and Cochrane Library up to March 2021 complemented by a manual search. Human longitudinal studies of >5 participants and at least 3 months follow-up were eligible for inclusion in the review.

WNT-5a and SOST Levels in Gingival Crevicular Fluid Depend on the Inflammatory and Osteoclastogenic Activities of Periodontal Tissues.

Wnt signaling leads to stimulation of osteoblasts and it reduces osteoclastogenesis and bone resorption via the regulation of the osteprotegrin and receptor activator of nuclear factor kappa-Β ligan (RANKL). Wnt signaling pathways are regulated by their physiological antagonists such as sclerostin (SOST) as well as WNT-5a. The aim of this study was to determine the total amount of Sclerostin and WNT-5a in the gingival crevicular fluid (GCF) in sites with a continuum from a healthy to diseased periodontium.

Strong Ground Motion Sensor Network for Civil Protection Rapid Decision Support Systems.

Strong motion sensor networks deployed in metropolitan areas are able to provide valuable information for civil protection Decision Support Systems (DSSs) aiming to mitigate seismic risk and earthquake social-economic impact. To this direction, such a network is installed and real-time operated in Chania (Crete Island, Greece), city located in the vicinity of the seismically active south front of the Hellenic Subduction Zone. A blend of both traditional and advanced analysis techniques and interpretation methods of strong ground motion data are presented, studying indicative cases of Chania shaking due to earthquakes in the last couple years.

Association between Periodontal Disease and Systemic Inflammatory Conditions Using Electronic Health Records: A Pilot Study.

Aims: To investigate the association between periodontal disease and systemic inflammatory conditions and examine the link between medical conditions and the extent of missing teeth in a large population.

Methods: In this retrospective study, a total of 4890 randomly selected patients who had attended the University of Minnesota dental clinics were analyzed. Severity of periodontal disease was determined based on the percentage of bone loss, evaluated through the examination of a full-mouth intraoral series of radiographs.

Evaluation of molecular and genetic predisposing parameters at diverticular disease of the colon.

Background: Diverticular disease (DD) refers to the presence of diverticula throughout the gastrointestinal (GI) tract, mainly along colon. DD might evolve into diverticulitis that is accompanied by severe clinical presentation, which includes abscess formation, perforation, stricture, obstruction and/or fistula.

Aim: The aim of the present review is to summarize the role of molecular and genetic factors in DD development, as well as their possible contribution towards new prognostic indicators, diagnostic algorithms and new therapeutic approaches.