Radiolabeling of cisplatin and its biodistribution in an experimental model of lung carcinogenesis.

This study optimized the radiolabeling of cisplatin with technetium-99m (99mTc) and evaluated its biodistribution in an experimental model of lung carcinogenesis. The percentage labeling of cisplatin with 99mTc was assessed using an ascending chromatographic technique. For biodistribution studies, male rats were divided into 2 groups.