PM anomaly detection for exceptional event demonstrations: A Texas case study.

The shifting frontiers of air pollution emission sources contribute to stagnation or reversal of air quality gains across the United States (US). The frequency and possible duration of Exceptional Events - driven primarily by wildfires and dust storms - have significantly increased in the US over the past decade. Combined with the US Environmental Protection Agency (EPA) final rule strengthening primary annual National Ambient Air Quality Standards (NAAQS) for PM by 25%, communities will need to reevaluate domestic and international sources of PM.

Despite Recovery from Necrotizing Enterocolitis Infants Retain a Hyperinflammatory Response to Injury.

Background: Necrotizing enterocolitis (NEC) is the leading gastrointestinal cause of death of premature neonates. NEC is associated with prematurity, a hyperinflammatory response, and dysregulation of intestinal barrier function. We hypothesize that patients with NEC will have, and continue to have after recovery, an increased hyperinflammatory intestinal response compared to those patients without NEC.

Persistent Proclivity to a Proinflammatory State in a Human Enteroid Model of Necrotizing Enterocolitis.

Necrotizing enterocolitis (NEC) is a devastating disease of premature neonates with substantial morbidity and mortality. Necrotizing enterocolitis is associated with prematurity, a hyperinflammatory response, and dysregulation of intestinal barrier function. We hypothesize that patients with NEC will have an increased hyperinflammatory intestinal response compared with those without NEC.