Publications by authors named "Charvet A"

Background: Global warming presents major public health challenges, with healthcare transportation significantly contributing to carbon dioxide equivalent emissions (eCO). While the greenhouse effects of anaesthetic gases are well-documented, the eCO of pre-anaesthesia consultations remains underexplored. This study aims to evaluate and propose strategies to reduce the carbon impact of these consultations at a Tertiary University Hospital.

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Purpose: To report on the oncological outcomes of active surveillance (AS) in low-grade prostate cancer (PCa) patients using the French SurACaP protocol, with a focus on long-term outcomes.

Methods: This multicenter study recruited patients with low-grade PCa between 2007 and 2013 in four referral centers in France. The cohort included patients meeting the SurACaP inclusion criteria, i.

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  • - This study investigates two strategies for initiating venoarterial extracorporeal membrane oxygenation (VA-ECMO) during lung transplantation (LTx) for patients with severe lung diseases, comparing an 'on-demand' approach versus a 'systematic' pre-emptive method.
  • - The trial will include adult patients needing bilateral LTx, excluding those with severe pre-existing conditions, and aims to identify which initiation strategy results in more ventilator-free days post-surgery.
  • - Outcomes will be assessed not only on ventilator-free days but also on various health metrics, like vital status at different intervals, while following ethical standards for patient care and data sharing.
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  • In minimally invasive thoracic surgery, paravertebral block (PVB) is a common technique for postoperative pain relief but relies heavily on the surgeon's skill and available resources, prompting a search for better methods when pain control fails.
  • The study aimed to compare the effectiveness of PVB performed by surgeons during video-assisted thoracoscopic surgery (PVB-VATS) against the traditional PVB technique done by anesthesiologists (PVB-US) to see if they produce similar pain management outcomes.
  • Conducted as a randomized clinical trial with 196 patients, the primary focus was on the differences in opioid consumption post-surgery, along with secondary measures such as pain scores
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Background: Fluid loading-based goal-directed therapy is a cornerstone of anaesthesia management in major surgery. Its widespread application has contributed to a significant improvement in perioperative morbidity and mortality. In theory, only hypovolemic patients should receive fluid therapy.

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Purpose: To report the long-term oncological outcomes of active surveillance (AS) in selected patients with favorable intermediate-risk (IR) prostate cancer (PCa).

Methods: A retrospective database review of two academic centers was conducted to identify favorable IR PCa patients initially managed by AS between 2014 and 2022. Favorable IR PCa was defined by the presence of one single element of IR disease (i.

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Purpose: To develop new selection criteria for active surveillance (AS) in intermediate-risk (IR) prostate cancer (PCa) patients.

Methods: Retrospective study including patients from 14 referral centers who underwent pre-biopsy mpMRI, image-guided biopsies and radical prostatectomy. The cohort included biopsy-naive IR PCa patients who met the following inclusion criteria: Gleason Grade Group (GGG) 1-2, PSA < 20 ng/mL, and cT1-cT2 tumors.

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The tension on the supply of surgical and FFP2 masks during the first wave of the COVID-19 pandemic leads to study the potential reuse of these masks. As washing is easily adaptable at home, this treatment solution was retained. In this work, thirty-six references of surgical masks and four FFP2 masks were tested without being worn or washed and after several washing cycles.

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Background: A significant number of patients admitted for aneurysmal subarachnoid hemorrhage (aSAH) are active smokers and are at risk of developing nicotine withdrawal symptoms (e.g., cravings, irritability, insomnia, headaches, etc.

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Purpose: Recently, Eggener et al. reignited a debate consisting to redefine Gleason Grade Group (GGG) 1 prostate cancer (PCa) as a precancerous lesion to reduce overdiagnosis and overtreatment. However, historical cohorts showed that some GGG1-labeled disease at biopsy may be underestimated by the standard PCa diagnostic workup.

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Background: Physiotherapy is a major cornerstone of enhanced rehabilitation after surgery (ERAS) and reduces the development of atelectasis after thoracic surgery. By initiating physiotherapy in the post-anaesthesia care unit (PACU), the aim was to evaluate whether the ultra-early initiation of rehabilitation (in the first hour following tracheal extubation) would improve the outcomes of patients undergoing elective thoracic surgery.

Methods: A case-control study with a before-and-after design was conducted.

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The need for personal protective equipment increased exponentially in response to the Covid-19 pandemic. To cope with the mask shortage during springtime 2020, a French consortium was created to find ways to reuse medical and respiratory masks in healthcare departments. The consortium addressed the complex context of the balance between cleaning medical masks in a way that maintains their safety and functionality for reuse, with the environmental advantage to manage medical disposable waste despite the current mask designation as single-use by the regulatory frameworks.

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Objective: To assess the contribution of maternal blood detection of IGFBP-1 for the diagnosis of amniotic-fluid embolism in clinical daily practice.

Design: A retrospective multicentre cohort study.

Setting: Three tertiary care obstetric units in France.

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  • The study examined the surgery benefits versus risks for octogenarians with early-stage non-small cell lung cancer (NSCLC) from 2005-2020, focusing on patient selection and outcomes.
  • Out of 100 patients, major complications occurred in 15, leading to 7 deaths, while factors like co-existing health issues significantly influenced recovery and survival rates.
  • Key findings included improved overall survival rates due to a specialized geriatric assessment pathway and the advantages of minimally invasive surgical techniques, suggesting effective treatment parallels with younger patients.
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The removal of airborne particles was investigated using a trickle granular bed. This filtration process maintains a constant pressure drop during particles loading, which makes it an interesting alternative for aerosol filtration. In order to establish mathematical models for the design of the process, a modelling approach that takes into account the changes of the bed characteristics due to the liquid hold up is undertaken.

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Given the prevalence and consequences of childhood obesity, efforts are being made to identify risk factors and design evidence-based interventions to reduce its impact. Food and beverage consumption habits are established early in life, making preschool-age children an important group to focus on. This cross-sectional study explored beverage intake and its association with body weight status among low-income preschool-age children enrolled in the Special Supplementation Nutrition Program for Women, Infants, and Children (WIC).

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The mechanical properties of injection molded plasticized cellulose acetate polymers processed with two different plasticizers (Triacetine and Diethyl phthalate) and various weight fractions comprised between 15 and 30 wt % have been investigated. Plasticized cellulose acetate exhibit a brittle-to-ductile transition from a low impact strength to a high impact strength of order 40 kJ/m². Obtaining a high impact resistance at room temperature requires plasticizer content larger than 25 wt.

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Iodine-containing contrast media (ICM) are extensively used to improve image quality and information content in x-ray-based examinations, particularly in computed tomography (CT). In parallel, there is increasing evidence that the use of ICM during CT sessions is associated with deoxyribonucleic acid (DNA) breaks that may influence the estimation of the risks linked to x-ray exposure. Why has iodine been preferred to any other heavy elements to enhance contrast in radiodiagnostics? How to understand such DNA breaks effect? We searched for the answers in the early times of x-ray medical use.

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  • Robotic assistance in early-stage non-small cell lung cancer surgery was compared to video-assisted surgery in terms of postoperative morphine consumption and patient health metrics.
  • The study involved 194 patients, with findings showing that those who underwent robotic surgery consumed more morphine (33 mg) compared to the video-assisted group (23 mg), indicating a statistically significant difference.
  • Additionally, robotic surgery was linked to worse haemodynamic and respiratory function than video surgery, raising concerns about its impact on patient recovery.
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  • - The study aimed to determine if using chlorhexidine gluconate (CHG) for oropharyngeal and nasopharyngeal decontamination could reduce respiratory complications following lung cancer surgery, similar to its effects observed in cardiac surgeries.
  • - In a trial with 474 lung cancer patients, 450 were analyzed after some withdrew consent, showing no significant difference in the need for postoperative mechanical ventilation or respiratory infections between those treated with CHG and those with a placebo.
  • - Although the CHG group had fewer cases of certain infections, like bacteremia and surgical-site infection, the trial found no substantial differences in overall health outcomes or hospital stays between the groups after surgery.
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Background: Obesity disproportionately affects children from low-income families and those from racial and ethnic minorities. The relationship between snacking and weight status remains unclear, although snacking is known to be an important eating episode for energy and nutrient intake particularly in young children. The purpose of this pilot study was to examine the snack intake of minority preschool children enrolled in the Head Start Program in four centers in Detroit, Michigan, and investigate differences by child weight status.

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Fibrous media embody the most effective and widely used method of separating ultrafine particles from a carrier fluid. The main problem associated with them is filter clogging, which induces an increasingly marked pressure drop with time and thus imposes regular media cleaning or replacement. This context has prompted the idea of investigating bubble columns, which operate at constant pressure drop, as alternatives to fibrous filters.

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The most effective and widely used dedusting techniques to separate nanoparticles of a carrier fluid are fibrous media. The main problem is the clogging of the filter that induces a pressure drop increase over time and thus requires a regular cleaning of the media (or its replacement). Following these observations, this study proposes to investigate the potential of bubble columns for nanoparticles collection.

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