Bortezomib is a frequently administered immunosuppressive agent in kidney transplantation. A 30-year-old male kidney transplant recipient developed an atypical reaction on the left hand in terms of spider-like extensions, indicating erythematous inflammation along the superficial veins after bortezomib intravenous administration. The inflammation spontaneously resolved after three weeks with a bortezomib dose reduction.
View Article and Find Full Text PDFAutoimmune diseases may act as a trigger for atypical hemolytic uremic syndrome (aHUS). Triggers for aHUS may include autoimmune diseases, infections, metabolic conditions, pregnancy, and transplants. aHUS-mediated injury to various organs, especially kidneys, can be life-threatening.
View Article and Find Full Text PDFBackground: Atypical hemolytic uremic syndrome (aHUS) is a rare disorder triggered by various stressors. Most of the time, stressors may not be identified in patients with aHUS. The disease may remain quiescent without manifestation throughout life.
View Article and Find Full Text PDFUnlabelled: The incidence of kidney disease patterns diagnosed by kidney biopsy depends on age, gender, race, socioeconomic, nutritional, and environmental factors. The present study was performed at a tertiary care teaching hospital in central India to show the current frequency of different types of kidney diseases through histopathological findings.
Materials And Methods: We carried out a retrospective analysis of kidney biopsies done in our institute between January 2016 and June 2021, and clinical and histopathological correlation was done from the available medical records.
The pattern of glomerular disease differs in incidence among the different geographical areas because of ethnicity, genetic variability, environmental factors, and socioeconomic conditions. The prevalence of pattern glomerular diseases varies from different parts of the world and from within the same country, the current study was performed to show the frequency of occurrence of primary and secondary glomerular disease (SGD) observed in a tertiary care hospital catering to patients from central India. In a retrospective study, we analyzed the clinical and pathological data of 176 kidney biopsies that were performed from 2016 to 2019 at the Department of Nephrology Super Speciality Hospital in Nagpur.
View Article and Find Full Text PDFSaudi J Kidney Dis Transpl
May 2020
Kimura's disease (KD) usually presents with a subcutaneous swelling and associated lymphadenopathy in the periauricular area. KD has a tendency to involve the kidneys. Proteinuria is reported in 12%-16% of cases, and around 60%-70% of them develop nephrotic range proteinuria.
View Article and Find Full Text PDFIn the absence of a national registry, the exact incidence and burden of chronic kidney disease in children in India is not known. The most common diagnosis for which children are likely to see a pediatric nephrologist is nephrotic syndrome constituting almost 40% of cases. Considering all the renal manifestations in the pediatric age group, we designed simply survey to find out the awareness among school going children about the kidney's function and dysfunction in our Indian scenario.
View Article and Find Full Text PDFSaudi J Kidney Dis Transpl
November 2019
Guillain-Barré syndrome (GBS) has been associated with both infective and noninfective etiologies. It is usually preceded by acute gastrointestinal or respiratory infections. We report an unusual case of GBS in a hepatitis C virus-positive hemodialysis (HD)-dependent patient who was being treated with sofosbuvir and daclatasvir along with antitubercular drugs for pulmonary tuberculosis.
View Article and Find Full Text PDFPrimary hyperparathyroidism (PHPT) usually presents with hypercalcemia related symptoms and signs. Kidneys play an important role in calcium homeostasis. PHPT has been reported to be associated with hyperchloremia, defective urinary acidification, and renal tubular acidosis (RTA).
View Article and Find Full Text PDFWe report a case of systemic lupus erythematosus (SLE) who presented with rapidly progressive renal failure (RPRF) with positive antinuclear antibody (ANA) and anti-double-stranded DNA (dsDNA) antibody and active urinary sediment in the form of microscopic hematuria and proteinuria. Provisional clinical diagnosis of lupus nephritis was made. Renal biopsy showed pauci-immune crescentic glomerulonephritis, the diagnosis of which was supported by positive serum anti-MPO antibody.
View Article and Find Full Text PDFEchinococcosis is a parasitic infection caused by the larval stage of a cestode and is endemic in sheep farming regions of developing countries. It manifests as hydatid cyst and most commonly is found in liver followed by lungs. Renal hydatid cyst is rare and amounts for 2% of all cases.
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