Patterns of prescription opioid dispensing among Red River Métis in Manitoba, Canada: a retrospective longitudinal cross-sectional study.

Background: Amid rising concern about opioid use across Canada, Métis leaders in Manitoba are seeking information on prescription opioid dispensing in Red River Métis populations to assist with planning and implementing appropriate evidence-based harm-reduction strategies in their communities. We examined patterns of prescription opioid dispensing among Red River Métis and compared them to those among other residents of Manitoba.

Methods: We conducted a population-based retrospective cross-sectional study for fiscal years 2006/07-2018/19 using administrative data from the Manitoba Population Research Data Repository and a study designed in partnership with researchers from the Manitoba Métis Federation.

Comparing patient-reported outcomes across countries: An assessment of methodological challenges.

Objectives: There is little published literature on the comparison of patient-reported outcomes between countries. This study aimed to assess pre- and postoperative health among samples of patients undergoing elective groin hernia repair procedures in the National Health Service (NHS), England, and groin hernia patients in Vancouver, Canada.

Methods: We used datasets from two different sources.

Culturally Responsive Supports for Metis Elders and Metis Family Caregivers.

Malgré une attention académique considérable au rôle de la famille des soignants avec la population générale, peu de recherches ont été menées avec les familles autochtones. Cette étude qualitative vise à combler cette lacune en se concentrant sur l'expérience des soignants Metis, fournir des soins aux adultes Metis plus âges. Des groupes de discussions et des entrevues ont été menés avec des aidants familiaux Metis (n - 79), aînés Metis (n - 11), et soignants officiels (n - 8).

A comparative analysis of NCLEX pass rates: Nursing health human resources considerations.

Aims: To examine performance differences among different writers of the National Council Licensure Examination-Registered Nurse (NCLEX-RN) examination in Canada; to compare Canadian and U.S. writer pass rate data; and to identify if changes in the Canadian nursing workforce can be related to the introduction of NCLEX-RN.

Photoelectron angular distributions from rotationally resolved autoionizing states of N.

The single-photon, photoelectron-photoion coincidence spectrum of N has been recorded at high (∼1.5 cm) resolution in the region between the N X Σg2, v = 0 and 1 ionization thresholds by using a double-imaging spectrometer and intense vacuum-ultraviolet light from the Synchrotron SOLEIL. This approach provides the relative photoionization cross section, the photoelectron energy distribution, and the photoelectron angular distribution as a function of photon energy.

Observations of high vibrational levels of the 4fσ4(1)Σu (+) state of H2.

Resonantly enhanced multiphoton ionization via the EF(1)Σg (+), v' = 6 double-well state has been used to probe the energy region below the third dissociation limit of H2 where several high vibrational levels of the 4(1)Σu (+) state are expected. Theoretical ab initio potential energy curves for this state predict a deep inner well and shallow outer well where vibrational levels above v = 8 are expected to exhibit the double-well character of the state. Since the 4(1)Σu (+) state has f-state character, transitions to it from the ground state are nominally forbidden.

Observations of the high vibrational levels of the B('')B̄ (1)Σ(u)(+) state of H2.

Double-resonance laser spectroscopy via the EF (1)Σg (+),v(')=6,J(')=0-2 state was used to probe the high vibrational levels of the B('')B̄ (1)Σu (+) state of molecular hydrogen. Resonantly enhanced multiphoton ionization spectra were recorded by detecting ion production as a function of energy using a time of flight mass spectrometer. New measurements of energies for the v = 51-66 levels for the B('')B̄ state of H2 are reported, which, taken with previous results, span the v = 46-69 vibrational levels.

Chestnut, American (Castanea dentata (Marsh.) Borkh.).

The key to successful transformation of American chestnut is having the correct combination of explant tissue, selectable markers, a very robust DNA delivery system, and a reliable regeneration system. The most important components of this transformation protocol for American chestnut are the following: starting out with rapidly dividing somatic embryos, treating the embryos gently throughout the Agrobacterium inoculation and cocultivation steps, doing the cocultivation step in desiccation plates, and finally transferring the embryos into temporary-immersion bioreactors for selection. None of these departures from standard Agrobacterium transformation protocols is sufficient by itself to achieve transgenic American chestnut, but each component makes a difference, resulting in a highly robust protocol.

Direct C-arylation of beta-enamino esters and ketones with arynes.

An efficient, mild, and general method for the C-arylation of beta-enamino esters and ketones with arynes has been developed. This methodology provides a facile and direct access to a variety of substituted aromatic beta-enamino compounds in moderate to excellent yield. [reaction: see text]

Survey of construction workers repeatedly exposed to chlorine over a three to six month period in a pulpmill: I. Exposure and symptomatology.

Objective: The admission to hospital of three construction workers with acute respiratory distress caused by inhalation of chlorine gas prompted the inspection of a building site located in a kraft pulpmill. The accidental emissions had taken place in the bleach plant and the construction workers assigned there were surveyed to uncover possible large scale health effects.

Design And Participants: A questionnaire was presented to 281 workers (participation rate = 97%); 257 workers reported an average of 24 exposure episodes to chlorine and derivatives over a three to six month period.

Improved cold-vapor atomic absorption technique for the microdetermination of total and inorganic mercury in biological samples.

An improved technique for the determination of inorganic and total mercury in human blood, hair, urine and tissue samples by the Magos methods, based on the use of a new reaction vessel, is described. With this vessel, the sample throughput is tripled, the amount of sample and concomitant reagents required are reduced by a factor of five, the precision, accuracy and sensitivity are measurably improved and the technique in amenable to automation.