Publications by authors named "Charnjeet S Sandhu"

Background: Anemia is a known risk factor for ischemic heart disease and serves as an independent predictor of major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS). This meta-analysis pools data from randomized controlled trials (RCTs) to better define hemoglobin (Hb) thresholds for transfusion in this setting.

Results: MEDLINE, EMBASE, and Cochrane databases were searched using the terms "Acute Coronary Syndrome" AND "Blood Transfusion" including their synonyms.

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We describe a case of 49-year-old man who presented with chest pain and was diagnosed with non-ST elevation myocardial infarction. Transthoracic echocardiogram (TTE) showed severe global hypokinesis of left ventricle with ejection fraction of 25%-30%. Left heart catheterisation showed severe right coronary stenosis and focal 60%-70% distal left anterior descending artery stenosis.

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A 31-year-old man with a recent diagnosis of hypothyroidism presented to the emergency department as a transfer from the clinic for severe hypotension and hypoglycaemia. The patient endorsed a 2-week history of severe fatigue, weight loss, nausea and non-bloody emesis. He was aggressively hydrated and vasopressors were initiated.

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Synopsis of recent research by authors named "Charnjeet S Sandhu"

  • - Charnjeet S Sandhu's recent research primarily focuses on cardiovascular health, particularly the effects of anemia and blood transfusion strategies in patients with acute coronary syndrome (ACS), contributing to evidence-based clinical guidelines.
  • - His meta-analysis work highlights the significance of defining hemoglobin thresholds for transfusion in ACS patients, indicating that optimal management of anemia can potentially improve outcomes and reduce major adverse cardiovascular events (MACE).
  • - Additionally, Sandhu has explored the outcomes of innovative procedures such as percutaneous left atrial appendage occlusion in the elderly, as well as the use of cerebral embolic protection during transcatheter aortic valve replacement, showcasing a commitment to improving interventional cardiology practices.