Publications by authors named "Charmie K Vang"

Article Synopsis
  • This study investigated a suspected outbreak of nontuberculous mycobacteria (NTM) among cystic fibrosis (CF) patients at the University of Texas Southwestern (UTSW) using genomic sequencing and epidemiological methods.
  • Whole-genome sequencing of 50 respiratory isolates revealed seven clusters of genetically similar NTM, with some evidence of potential healthcare-associated transmission within three clusters.
  • The findings suggest that while person-to-person transmission within the healthcare setting is rare, patients may be acquiring infections from multiple sources outside of the hospital environment.
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Outbreaks of nontuberculous mycobacteria (NTM) among people with cystic fibrosis (pwCF) have been reported at CF centers with conflicting conclusions. The occurrence of NTM at the UVMC (University of Vermont Medical Center) adult CF program was investigated. Use the HALT NTM (Healthcare-associated Links in Transmission of NTM) toolkit to investigate the healthcare-associated transmission and/or acquisition of NTM among pwCF having genetically similar NTM isolates.

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Aims: Mycobacterium abscessus subsp. abscessus (MABS) is an emerging, opportunistic pathogen found globally in freshwater biofilms and soil. Typically, isolates are treated as a uniform group of organisms and very little is known about their comparative survival in healthy host cells.

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Free-living amoebae are ubiquitous in aquatic environments and act as environmental reservoirs for nontuberculous mycobacteria. subsp. recovered from has been demonstrated to be more virulent in both human and murine models.

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