A Comparative Study Evaluating the Efficacy of Lignocaine and Dexmedetomidine with Lignocaine and Adrenaline in Third Molar Surgery.

Aim: The aim of this study was to compare the anesthetic efficacy, duration of action, pain, and cardiovascular effects of dexmedetomidine when added to 2% lignocaine hydrochloride in bilateral symmetrical impacted third molars.

Materials And Methods: This study comprised of 40 healthy patients who required extraction of identical bilateral impacted lower third molars. The left side of the patients was designated as test side where patients received local anesthesia with lignocaine plus dexmedetomidine (2% lignocaine + dexmedetomidine 1 μ/ml), and the right side of the patients was designated as control side where patients received local anesthesia with lignocaine plus adrenaline (2% lignocaine in 1:80,000 adrenaline).