Publications by authors named "Charlotte Robitaille"
Article Synopsis
- A 40-year-old man with autoimmune encephalitis and a thymoma experienced severe neurological symptoms and multiple relapses despite initial treatments, which included thymectomy and first-line immunotherapy.
- Initial antibody tests revealed acetylcholine receptor and titin antibodies, but further testing eventually identified anti-GABA receptor antibodies.
- The case highlights the challenge of diagnosing and treating autoimmune encephalitis with coexisting antibodies, underscoring the need for targeted second-line therapies like rituximab in severe cases.
Background: Myocardial infarction (MI) has been shown to induce fibrotic remodelling of the mitral and tricuspid valves. It is unknown whether MI also induces pathological remodelling of the aortic valve and alters aortic stenosis (AS) progression. We thus compared AS progression after an acute MI and in patients with/without history of MI, and assessed post-MI pathobiological changes within the aortic valve leaflets in a sheep model.
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