Publications by authors named "Charlotte Pierrat"

Background: Monitoring the HIV epidemic in a defined population is critical for planning treatment and preventive strategies. This is especially important in sub-Saharan Africa, which harbours the highest burden of the disease.

Objective: To estimate HIV incidence in adults aged 18-47 years old and to investigate spatial variations of HIV prevalence in Manhiça, a semi-rural area of southern Mozambique.

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Article Synopsis
  • * The study analyzed genetic differences in parasite alleles between infected mothers and their infants, using both genetic comparisons and Geographic Information System (GIS) tools to assess the distribution of these alleles.
  • * Results indicated that infants exposed to specific glurp alleles from placental malaria are more susceptible to infections carrying the same alleles, regardless of where they lived, highlighting the significance of these alleles in early malaria infections.
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Malaria remains endemic in tropical areas, especially in Africa. For the evaluation of new tools and to further our understanding of host-parasite interactions, knowing the environmental risk of transmission--even at a very local scale--is essential. The aim of this study was to assess how malaria transmission is influenced and can be predicted by local climatic and environmental factors.

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Background: The association between placental malaria (PM) and first peripheral parasitaemias in early infancy was assessed in Tori Bossito, a rural area of Benin with a careful attention on transmission factors at an individual level.

Methodology: Statistical analysis was performed on 550 infants followed weekly from birth to 12 months. Malaria transmission was assessed by anopheles human landing catches every 6 weeks in 36 sampling houses and season defined by rainfall.

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