Preserved cortical thickness, surface area and volume in adolescents with PTSD after childhood sexual abuse.

Exposure to childhood adverse events is associated with severe consequences for general health and structural and functional changes in the brain of its survivors. In order to unravel and in the end influence the pathway linking adversity and pathology, neuroimaging research is crucial. Up till now studies in minors are scarce and differ in type of adversity or methodology.

Cross-reactivity between darunavir and trimethoprim-sulfamethoxazole in HIV-infected patients.

Objective: Both darunavir (DRV) and trimethoprim-sulfamethoxazole (TMP-SMX) carry a sulfonamide moiety and a warning for this cross-reactivity is given in the label of DRV. The aim of this study was to investigate the potential cross-reactivity between both drugs.

Design: Retrospective cohort study with a nested case-control study.