Particulate inorganic adjuvants: recent developments and future outlook.

Objectives: To review the state of the art and assess future potential in the use of inorganic particulates as vaccine adjuvants.

Key Findings: An adjuvant is an entity added to a vaccine formulation to ensure that robust immunity to the antigen is inculcated. The inclusion of an adjuvant is typically vital for the efficacy of vaccines using inactivated organisms, subunit and DNA antigens.