Publications by authors named "Charlotte Leroy"

Background: Pregnant women are more vulnerable to the severe effects of COVID-19 compared to their non-pregnant peers. Early in the pandemic, there was a rise in cesarean deliveries and preterm births among infected pregnant women. This study aims to evaluate whether there were any changes in obstetric interventions during the first two waves of the pandemic in Belgium.

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Background: Trial of Labor After Cesarean is an important strategy for reducing the overall rate of cesarean delivery. Offering the option of vaginal delivery to a woman with a history of cesarean section requires the ability to manage a potential uterine rupture quickly and effectively. This requires infrastructure and organization of the maternity unit so that the decision-to-delivery interval is as short as possible when uterine rupture is suspected.

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Aim: Pharyngeal leak (PL) and pharyngocutaneous fistula (PCF) are serious complications following total laryngectomy and their incidence is higher in the salvage setting. The aim of this study is to describe the accuracy of water soluble swallow (WSS) to rule out salivary postoperative leak after salvage total laryngectomy (STL) to expedite start of oral intake.

Material And Methods: Retrospective study including patients undergoing STL between 2008 and 2021 at Guy's Hospital.

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Article Synopsis
  • HPV-positive and negative oropharyngeal cancers have different characteristics, but their post-therapeutic surveillance (PTS) methods are currently similar, leading to potential changes in practice that need acceptance from both doctors and patients.
  • The study surveyed 133 HPV-positive patients and 90 physicians involved in cancer treatment, revealing that while patients hesitate to adopt new PTS options, a significant majority supports using HPV circulating DNA (Ct DNA) for monitoring.
  • Both patients and physicians recognize the need for tailored PTS strategies based on HPV status, with a strong interest in clinical trials to test new monitoring approaches that involve HPV Ct DNA levels.
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  • A retrospective study in Belgium assessed pregnancy outcomes following the adoption of IADPSG/WHO guidelines, comparing periods before and after the guidelines were implemented.
  • The study found that while hyperglycemia in pregnancy (HIP) prevalence increased significantly, some adverse outcomes like gestational weight gain, hypertension, and neonatal intensive care admissions decreased across the population.
  • Notably, complications such as emergency cesarean sections and preterm births rose overall, although outcomes related to HIP showed improvement, suggesting a complex relationship between guidelines and maternal-fetal health.
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Introduction: Although Human Papilloma Virus (HPV)-driven oropharyngeal cancer (OPC) prognosis is significantly better than that of other head and neck cancers, up to 25% of cases will recur within 5 years. Data on the pattern of disease recurrence and efficiency of salvage treatment are still sparse.

Material And Method: Observational study of all recurrent OPCs diagnosed, following a curative intent treatment, in seven French centers from 2009 to 2014.

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Introduction: HPV-driven oropharyngeal cancer (OPC) patients have a better prognosis than their HPV-negative counterparts but several studies have suggested that among HPV-positive patients those with a smoking history had worse oncological outcomes. The aim of our study is to characterize the interplay between tobacco consumption, patient and disease characteristics, and disease control.

Materials And Methods: All patients diagnosed with HPV-driven OPC and treated with curative intent between 2007 and 2009 and 2011-2016 at Gustave Roussy cancer center were included (n = 282).

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Objectives: To investigate the effect of maternal origin on the association between maternal height and the risk of preterm birth (PTB).

Design: Retrospective observational cohort study.

Setting: Two of the three Belgian regions, including Brussels-Capital and Walloon regions.

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Extracting coherent wavefronts between passive receivers using cross-correlations of ambient noise (CAN) provides a means for monitoring the seismoacoustic environment without using active sources. However, using cross-correlations between single receivers can require a long recording time in order to extract stable coherent arrivals from CAN. This becomes an issue if the propagation medium fluctuates significantly during the recording period.

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