Publications by authors named "Charlotte Heald"
Article Synopsis
- Recent findings suggest that variants in the prostate specific antigen (PSA) gene may raise the risk of prostate cancer (PC), particularly the G/A substitution in the androgen response element (ARE) region.
- In a study involving 100 PC patients, 79 benign prostate hyperplasia (BPH) cases, and 67 controls, researchers analyzed DNA from blood samples to assess the relationship between PSA polymorphisms and PC risk.
- The study revealed a higher prevalence of the GG genotype in PC patients, especially in younger men, and confirmed that having a short CAG repeat in combination with the GG genotype significantly increases the likelihood of developing prostate cancer.
