[COPD exacerbation: towards a blood eosinophil-guided corticosteroid therapy?].

Measurement of blood eosinophils helps identify COPD patients at increased risk of acute exacerbation who would benefit from the initiation of maintenance therapy with inhaled corticosteroids. This strategy has been included into the GOLD recommendations. Would there be an interest in measuring blood eosinophils to manage COPD exacerbations? Recently, strategies using blood eosinophil count have been developed to better target the group of patients with exacerbations who respond to systemic corticosteroid therapy and also to limit its prescription when the risk/benefit ratio is unfavorable.

High-flow nasal oxygen in acute hypoxemic respiratory failure: A narrative review of the evidence before and after the COVID-19 pandemic.

High-flow nasal oxygen (HFNO) is a type of non-invasive advanced respiratory support that allows the delivery of high-flow and humidified air through a nasal cannula. It can deliver a higher inspired oxygen fraction than conventional oxygen therapy (COT), improves secretion clearance, has a small positive end-expiratory pressure, and exhibits a washout effect on the upper air space that diminishes dead space ventilation. HFNO has been shown to reduce the work of breathing in acute hypoxemic respiratory failure (AHRF) and has become an interesting option for non-invasive respiratory support.

[Etiological diagnosis of thyroid nodules : collaborative approach between the internist and specialists].

One or more thyroid nodules, most often asymptomatic, may be found in more than half of the population, and they usually do not require specific therapeutic management, except for cancerous nodules. In order to avoid under-diagnosis and over-treatment, we propose a diagnostic strategy in line with current recommendations, based on the collaboration between general internist, radiologist, and endocrinologist. In addition to clinical information and thyroid function tests, thyroid ultrasound remains the first step in assessing the risk of nodule malignancy and setting the indication for fine needle aspiration.