Publications by authors named "Charlotte E Laupheimer"
Regul Toxicol Pharmacol
October 2024
Article Synopsis
- The study calculates a tolerable intake (TI) for vanadium concerning chronic exposure in implantable medical devices, following the updated ISO 10993-17:2023 standards, which introduced new uncertainty factors.
- The research found a TI of 0.20 μg V/kg/day based on ISO guidance and a Permissible Daily Exposure (PDE) of 0.24 μg V/kg/day according to ICH guidance, with the latter being seen as a more practical estimate.
