Abdominal Drainage in Complicated Appendicectomy - Resources Down the Drain?

Background: There is currently no clear consensus on the use of drains during an appendicectomy to prevent abscess formation. Our aim was to ascertain whether the use of drains in complicated appendicitis reduces post-operative complications and length of stay.

Methods: We performed a retrospective review of patients with complicated appendicitis undergoing appendicectomy from March-November 2018.

General surgeon's antibiotic stewardship: Climbing the Rogers Diffusion of Innovation Curve-Prospective Cohort Study.

Introduction: The primary aim of this study was to establish concordance of general surgeon's prescribing practice with local IV-oral antibiotic guidelines. The secondary aim was to evaluate the effect of introducing educational antibiotic measures. The Rogers Diffusion of Innovation Model was used to explore the adoption of antibiotic stewardship practices.

Transcriptional profiling identifies the long noncoding RNA plasmacytoma variant translocation (PVT1) as a novel regulator of the asthmatic phenotype in human airway smooth muscle.

Background: The mechanism underlying nonsevere and severe asthma remains unclear, although it is commonly associated with increased airway smooth muscle (ASM) mass. Long noncoding RNAs (lncRNAs) are known to be important in regulating healthy primary airway smooth muscle cells (ASMCs), whereas changed expression has been observed in CD8 T cells from patients with severe asthma.

Methods: Primary ASMCs were isolated from healthy subjects (n = 9) and patients classified as having nonsevere (n = 9) or severe (n = 9) asthma.

Co-operation with pre-operative cardiovascular monitoring amongst children for chair dental general anaesthesia.

Introduction: The Association of Anaesthetists of Great Britain and Ireland (AAGBI) guidelines Recommendations for standards of monitoring during anaesthesia and recovery state that cardiovascular monitoring for induction of general anaesthesia should include pulse oximetry and non-invasive blood pressure measurement, but recognise that young patients may not co-operate sufficiently to allow this. The aim of this study was to look at levels of compliance possible for pulse oximetry and non-invasive blood pressure measurement, in a population known to be unco-operative with therapeutic interventions.

Patients And Methods: A retrospective review of 500 records of patients attending for chair dental general anaesthesia was carried out.

Mental nerve anaesthesia; a complication of sickle cell crisis during childbirth.

This report describes the case of an Afro-Caribbean lady diagnosed with sickle cell anaemia, who presented with permanent mental nerve anaesthesia as a result of a sickle cell crisis during childbirth.